A new system proposed for the generation of radioisotopes with accelerator neutrons by deuterons (GRAND) is described by mainly discussing the production of 99 Mo used for nuclear medicine diagnosis. A prototype facility of this system consists of a cyclotron to produce intense accelerator neutrons from the nat C(d,n) reaction with 40 MeV 2 mA deuteron beams, and a sublimation system to separate 99m Tc from an irradiated 100 MoO 3 sample. About 8.1 TBq/week of 99 Mo is produced by repeating irradiation on an enriched 100 Mo sample (251 g) with accelerator neutrons for two days three times. It meets about 10% of the 99 Mo demand in Japan. The characteristic feature of the system lies in its capability to reliably produce a wide variety of high-quality, carrier-free, carrier-added radioisotopes with a minimum level of radioactive waste without using uranium. The system is compact in size, and easy to operate; therefore it could be used worldwide to produce radioisotopes for medical, research, and industrial applications.
Our results suggest that the causative P. aeruginosa strains in cases of infectious keratitis associated with CL wear originate in contaminated CL storage cases. However, it is still unclear whether the environmental strains in the patients' houses also cause keratitis.
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