Ferrihemoproteins in buffer solutions bind nitric oxide to yield their nitric oxide adducts. Reversible binding of NO was found for ferricytochrome c (Cyt III ) and metmyoglobin (Mb III ) at pH values lower than ca. 7.0. The equilibrium constants were obtained as (1.6 ( 0.1) × 10 4 M -1 for Cyt III and (1.3 ( 0.1) × 10 4 M -1 for Mb III . At higher pH, the reversible formation of the NO adducts is no longer observed; the NO adduct of Cyt III (Cyt III -NO) undergoes reduction to ferrocytochrome c, Cyt II , and that of Mb III (Mb III -NO) to the nitrosyl adduct of Mb II (Mb II -NO). Methemoglobin (Hb III ) reacts readily with NO even at pH < 6 to give the nitrosyl adduct of hemoglobin (Hb II -NO). The rates for the formation of Cyt II , Mb II -NO, and Hb II -NO were measured as functions of NO and OHconcentrations. Kinetic analysis indicates that Cyt III -NO and Mb III -NO undergo nucleophilic attack by OHat higher pH to yield Cyt II and Mb II , respectively. Mb II thus produced further reacts with NO to give Mb II -NO. For Hb III , the nitrosyl adduct (Hb III -NO) was found to react with both OHand H 2 O to give Hb II -NO in the presence of excess NO. The rate constants for the reaction between the nitrosyl ferrihemoproteins and OHwere determined as (1.5 ( 0.1) × 10 3 M -1 s -1 for Cyt III -NO, (3.2 ( 0.2) × 10 2 M -1 s -1 for Mb III -NO, and (3.2 ( 0.2) × 10 3 M -1 s -1 for Hb III -NO. The reductive nitrosylation of Hb III observed at pH < 6.0 is explained by reaction of H 2 O with Hb III -NO: the rate constant is (1.1 ( 0.1) × 10 -3 s -1 . 5702

We describe the asymptotic behavior of small energy solutions of an NLS with a trapping potential generalizing work of Soffer and Weinstein, and of Tsai and Yau. The novelty is that we allow generic spectra associated to the potential. This is yet a new application of the idea of interpreting the nonlinear Fermi Golden Rule as a consequence of the Hamiltonian structure.

we analyze rigorously and with great detail the interaction of a solition of the Nonlinear Schroedinger equations with a nontrapping potential in the case when the soliton moves at large speed

We investigate the minimizers of the energy functionalunder the constraint of the L

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