No abstract

No abstract

To elucidate the biological effect of static magnetic fields (SMF), we measured lipid peroxidation in the liver, kidneys, heart, lungs and brain of mice exposed to SMF and also evaluated the combined effect of SMF exposure on the hepatotoxicity induced by treatment with carbon tetrachloride (CC14). Lipid peroxidation in the liver was significantly increased by exposure to 4.7 T of SMF for 3, 6, 24, or 48 h, whereas that in the kidneys, heart, lungs and brain was not changed compared to the control. The combination of CC14 injection and SMF exposure caused an increase in lipid peroxidation in the liver exceeding that caused by either treatment alone. Furthermore, the increase in activities of both GOT and GPT caused by CC14 administration were also enhanced by SMF exposure. These results indicate that the exposure to strong SMF induces lipid peroxidation in the liver of mice and enhances the hepatotoxicity caused by CC14 administration.

No abstract

In this study, the effects of 5-tesla (T) static magnetic fields (SMFs) on food and water intake in BALB/c mice were examined. We also examined body weight changes, organ weights and some serum biochemical parameters to evaluate the physiological changes resulting from changes in food and water intake. Mice were exposed to 5-T SMFs for 24 h and 48 h. by food intake, water intake, and body weight of the mice. However, the weights of brain, lungs, heart, liver, spleen, and kidneys did not change after 48 h of exposure. The blood urea nitrogen (BUN) levels and blood glucose levels increased significantly after 48 h of exposure (p = 0.03, p = 0.005, respectively). The BUN-to-creatinine (BUN/Cr) ratio tended to increase after 48 h of exposure (p = 0.07).We conclude that exposure to 5-T SMFs for 48 h suppresses eating and drinking behavior. We considered that the decreased body weight, increased BUN levels and slightly increased BUN/Cr ratio after 48 h of exposure to 5-T SMFs were due to body fluid loss resulting from decreased food and water intake.