Ultrasound (US) and magnetic resonance imaging (MRI) are two modalities for diagnosing fetal gastrointestinal (GI) anomalies. Ultrasound (US) is the modality of choice. MRI can be used as a complementary method. Despite its expanding utilization in central nervous system (CNS) fetal malformation, MRI has not yet been established for evaluation of fetal GI abnormalities. Therefore, more attention should be paid to the clinical implications of MRI investigations following screening by US.
Background: Breast cancer may result in remodeling of adjacent normal appearing breast tissues. Magnetic resonance imaging (MRI) is increasingly used in the diagnosis and follow-up of breast cancer by means of diffusion weighted imaging, which is based on thermal motion of water molecules in the extracellular fluid. Objectives: We investigated the correlation of visual assessment of peri-tumoral edema with peri-tumoral and tumoral apparent diffusion coefficient (ADC) values. Patients and Methods: In this cross-sectional study, from 2016 to 2018, 78 patients with 89 malignant breast lesions (mean age, 47 years) were examined by 1.5-T breast MRI. The lesions were categorized based on the visual assessment of peri-tumoral edema on T2 weighted imaging (T2WI) into two groups: (A) with edema (36 lesions) and (B) without edema (53 lesions). Measuring ADC values in the contralateral normal breast tissue, peri-tumoral tissue and peri-tumoral-normal tissue ADC ratio were compared between the two groups for all lesions. Results: The number of in situ lesions was higher in group B (7.5% vs 2.7%) with the p value of 0.01. The mean of ADC values in the normal breast tissue was 1.76 × 10-3mm2/s. Tumor ADCs were significantly lower in group A compared to group B (0.95 × 10-3mm2/s vs. 1.11 × 10-3mm2/s) with the P value of 0.003. However, peri-tumoral ADCs were significantly higher in group A (1.82 × 10-3mm2/s vs. 1.53 × 10-3mm2/s) with the p value of 0.005. The peri-tumoral-normal tissue ADC ratio was 0.87 in group B and about 1 in group A. However, the difference between normal tissue ADCs and peri-tumoral ADCs was only significant (P value of 0.005) in group B. The cut-off point value for differentiating normal tissue ADCs and peri-tumoral ADCs was 1.61 × 10-3mm2/s with the sensitivity of 65% and specificity of 70%. Conclusion: Breast cancer with peri-tumoral edema has lower tumoral ADC values, higher peri-tumoral ADC values and lower prevalence of in situ lesions. Visual assessment of peri-tumoral edema on T2WI could predict the tumoral characteristic on diffusion-weighted imaging.
Uterine Arteriovenous malformations (AVM) are vascular disorders characterized by complex high‐flow tangles of abnormal vessels connecting arteries and veins with bypassing capillaries. Recently, the terminology applied to describe uterine AVMs has been modified. Most AVMs are acquired. The term enhanced myometrial vascularity (EMV) is used to describe any condition in which any uterine pathology may lead to increased myometrial vascularity regardless of the absence or presence of residual tissue of gestation.
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