BackgroundDamage to the cerebellum may lead to motor dysfunctions, but also to the neuropsychological deficits that comprise the Cerebellar Cognitive Affective Syndrome (CCAS). It can affect executive functions, attention, memory, visuospatial functions, language, and emotions. Our goal was to determine which neuropsychological tests could be effectively used to identify this syndrome during a short examination.MethodsTwenty-five patients with an isolated cerebellar lesion and 25 matched healthy controls were examined using an extensive neuropsychological battery.ResultsLogistic regression models and sub-models were computed for individual tests, as well as for the full battery. The best results were produced by a model combining patient education level, the number of errors on the California Verbal Learning Test, and time on Prague Stroop Test (Dots).ConclusionsBased on the results, we suggest that a condensed battery of neuropsychological tests can be used to detect CCAS. The tests are easy to administer and could be helpful in both research and clinical settings.Electronic supplementary materialThe online version of this article (doi:10.1186/s40673-017-0071-9) contains supplementary material, which is available to authorized users.

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There are many optimization heuristics which involves mutation operator. Reducing them to binary optimization allows to study properties of binary mutation operator. Modern heuristics yield from Lévy flights behavior, which is a bridge between local search and random shooting in binary space. The paper is oriented to statistical analysis of binary mutation with Lévy flight inside and Quantum Tunneling heuristics.

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