Temporary improvement of atopic dermatitis lesions may occur after acute, severe infections. One such case is shortly described, and it is then proposed that such a phenomenon may serve as an indirect evidence to support the finding of a predominant Th2 imbalance in atopic dermatitis.
Lichen nitidus (LN) is a benign micropapular eruption of unknown etiology that often follows an unpredictable course. LN typically affects children and young adults and presents with asymptomatic, discrete, uniform, skin colored, pin-point sized papules.1 These papules are commonly found on the chest, abdomen, flexor surfaces of the upper extremities, dorsal hand, and anogenital region.1 Focal presentation is more common while generalized distribution of LN is rarer and seen more exclusively in pediatric patients.2 Although patients are typically asymptomatic, pruritus is sometimes a noted symptom.1 We report the diagnosis and treatment of an uncommon case of generalized LN in a middle-aged adult.
When a newborn exhibits dermal aplasia on the face and neck, especially if there are ocular anomalies, further investigation is needed to determine if they have MiDAS (microphthalmia, dermal aplasia, and sclerocornea) or other syndromes with associated skin findings. It is essential to diagnose MiDAS syndrome early in life to allow for thorough workup to determine if there are any associated abnormalities in the child that require treatment. While the skin lesions of MiDAS syndrome heal spontaneously, other associated abnormalities require early intervention and can be life threatening.
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