These results indicate that CpG ODN might be an effective mucosal adjuvant, acting by mechanisms that are different from CT. These findings suggest that nasal vaccination with P6 and CpG ODN might be an effective regimen for the induction of NTHi-specific protective immunity.

These findings suggest that survivin may act as a major cancer antigen in head and neck cancer. Anti-survivin antibody responses may be a valuable marker in patients with head and neck cancer.

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The purpose of this study was to compare with the effects of vestibular rehabilitation (VR) for peripheral vertigo (PE group) and psychogenic vertigo (PS group) patients. [Subjects] A total of 25 patients with vertigo (PS group: 9 persons, PE group: 16 persons) participated in this study. [Methods] The severity of vertigo scale (SV), Berg Balance Scale (BBS) and Dizziness Handicap Inventory Japanese version (DHI-J) were used to assess the vertigo or dizziness symptoms and handicaps before and after the intervention. [Results] VR had a high effect on all of the assessments in the PE group, whereas effects on autonomic nervous symptoms and DHI-Emotional (DHI-E) were moderate, and DHI-Functional (DHI-F) was small, in the PS group. [Conclusion] The results suggest that VR might be effective at improving SV, BBS and DHI-J in PS cases, and symptoms of vertigo, BBS and DHI-P in PE cases.