Introduction: The family is the fundamental group to increase the health status of the elderly as it promotes well-being and psycho-emotional development in which depression is considered a public health problem that involves not only family intervention but also that of the Health sector. Objective: To determine the relationship between depression and family functioning in the elderly who goes to a second-level health care unit in Cd Victoria Tamaulipas, Mexico. Methodology: Quantitative, descriptive-cross-sectional and correlational study with 139 elderly adults in a local health institution using simple random probabilistic sampling, through interview and application of the family Apgar and Yesavage scale. Results: Average age 68.14 years, female predominance 63%, with primary schooling 87%. with absence of depressive symptomatology 80%, 81% under a norm functional family environment. Conclusion: If there is a relationship between both variables.