The research for this study examined the extent to which organisational factors, represented by perceived organisational support and workplace incivility, and individual factors, represented by core self-evaluation (CSE), predicted intrapreneurship. The key hypothesis was that CSE would be associated with intrapreneurship and that incivility and perceived organisational support would serially mediate this relationship. Participants were 410 working adults who volunteered to complete a series of questionnaires measuring CSE, incivility, perceived organisational support, and intrapreneurship. Analysis showed a serial mediation effect between CSE and intrapreneurship through incivility and perceived organisational support. By integrating both individual and organisational antecedents of intrapreneurship from the perspective of CSE, the research illustrates the significant role CSE plays in determining to what extent intrapreneurial behaviours will be exhibited. Findings from this study provide insights for both organisations and researchers in determining the fundamental relationships between individual and organisational factors in predicting intrapreneurial behaviours.