Background: The ingestion of large amounts of milk and antacids to treat peptic ulcer disease was a common cause of hypercalcemia in the past (the “milk-alkali syndrome”). The current popularity of calcium and supplements has given rise to a similar problem. Objectives: To evaluate the prevalence and characteristics of hypercalcemia induced by calcium intake (“calcium supplement syndrome”; or CSS) in hospitalized patients. Methods: We conducted a retrospective; electronic health record (EHR)-based review of patients with hypercalcemia over a 3-year period. Diagnosis of CSS was based on the presence of hypercalcemia; a normal parathyroid hormone (PTH) level; renal insufficiency; metabolic alkalosis; a history of calcium intake; and documented improvement with treatment. Results: Of the 72 patients with non-PTH mediated hypercalcemia; 15 (20.8%) satisfied all the criteria for the diagnosis of CSS. Calcium; vitamin D; and multivitamin ingestion were significantly associated with the diagnosis (p values < 0.0001; 0.014; and 0.045 respectively); while the presence of hypertension; diabetes; and renal insufficiency showed a trend towards statistical significance. All patients received intravenous fluids; and six (40%) received calcium-lowering drugs. The calcium level at discharge was normal 12 (80%) of patients. The mean serum creatinine and bicarbonate levels decreased from 2.4 and 35 mg/dL on admission respectively; to 1.6 mg/dL and 25.6 mg/dL at discharge respectively. Conclusion: The widespread use of calcium and vitamin D supplementation can manifest as hypercalcemia and worsening of kidney function in susceptible individuals. Awareness among health care professionals can lead to proper patient education regarding these health risks.

IDVCs are a risk factor for NTM BSI. Sickle cell anaemia appears to be a risk factor for IDVC infections due to NTM. This study is limited by the small sample size. A larger study is needed to further investigate the association between HbSS/SC and NTM IDVC infections.

The term Ethnobotany describes the study of people's relationships to plants as foods, fibers, medicines, dyes, and tools throughout the ages. Using the student active technique of experiential learning, undergraduate students enrolled in landscape design and implementation classes at Clemson University planned and installed an Ethnobotany garden in partnership with the South Carolina Botanical Garden (SCBG) staff, volunteers, and Sprouting Wings children. Sprouting Wings is an after-school gardening and nature exploration program for under-served elementary school students. College students and faculty working on this service-learning project contributed over 1,000 hours to their community while learning more about both the art and the science of landscape design and implementation. Students enrolled in the landscape Implementation class were surveyed to evaluate their perceptions on a variety of possible learning outcomes for this class. Students indicated that their service learning experience with the Ethnobotany project allowed them to acquire and practice new skills, broadened their understanding of the surrounding community, increased their ability to work in real world situations, introduced new career possibilities, gave students a better understanding of their course work, increased their ability to work on a team, increased their knowledge of environmental sustainability, and allowed them to discover or develop leadership capabilities. In a survey question regarding preference for service learning rather than traditional classes, the majority of students prefer the service learning pedagogy. In addition, most students reported a high degree of initiative for this project in their reflections.

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