Objective: Acne vulgaris, a chronic disorder of pilosebaceous units, is common in adolescents. Early detection and appropriate treatment of acne is essential in the prevention of severe acne and scarring, and the consequent adverse psychosocial disabilities resulting from feelings of embarrassment, frustration and poor self-esteem. Emotional issues in young individuals with acne must be identified appropriately. Material and method: This was a cross-sectional survey involving students applied to a University Medical Center. They were administered a questionnaire including socio-demographical properties, general knowledge about acne and Rosenberg Self-Esteem Scale's first ten questions. SPSS 15.0 program was used for statistical analysis and p<0.05 was accepted as statistical significant. Results: Two hundred and forty seven students were included and 63.6% (n.157) were women. Mean age was 21.40±2.38. Majority of the students (99.3%) had acne but 41.3% of acne problems had lasted before three months. Acne was defined as an illness by 53.4% of the students and 38.1% visited a doctor for acne treatment. Conclusion: Despite the high prevalence of acne, there is still much deficiency of knowledge and wrong beliefs about acne. This indicates that there is a need for education about etiopathogenesis, potential complications and importance of effective treatment for acne.