Background:There are limited data comparing the prognosis and fertility outcomes of the patients with early cervical cancer treated by trans-vaginal radical trachelectomy (VRT) or abdominal radical trachelectomy (ART).The objective of this study was to compare the surgical and pathologic characteristics, the prognosis and fertility outcomes of the patients treated by VRT or ART.Methods:Matched-case study based on a prospectively maintained database of patients underwent radical trachelectomy in 10 centres of China was designed to compare the prognosis and fertility outcomes of the patients treated by VRT or ART.Results:Totally 150 cases, 77 in the VRT and 73 in the ART group, were included. VRT and ART provide similar surgical and pathological outcomes except larger specimens obtained by ART. In the ART group, no patient developed recurrent diseases, but, in the VRT group, 7 (9.8%) patients developed recurrent diseases and 2 (1.6%) patients died of the tumours (P=0.035). The rate of pregnancy in the VRT group was significantly higher than those of ART (39.5% vs 8.8% P=0.003). The patients with tumour size >2 cm showed significant higher recurrent rate (11.6% vs 2.4%, P<0.05) and lower pregnant rate (12.5% vs 32.1%, P=0.094) compared with the patients with tumour size <2 cm.Conclusion:Patients treated by ART obtained better oncology results, but their fertility outcomes were unfavourable compared with VRT. Tumour size <2 cm should be emphasised as an indication for radical trachelectomy for improving the outcome of fertility and prognosis.
The discovery that polyethylene oxide promotes ionic conductivity led to the development of solid polymer electrolytes. However, their conductivity is severely reduced by crystallinity. Here, statistical copolymerization is used to design macromolecular architectures where crystallinity is disrupted by a minimal amount of non-ethylene oxide comonomer units. Using the Flory exclusion model, we demonstrate that polymers containing 18 mol% comonomer and 18 wt% LiTFSI are devoid of crystallinity. A 10 mol% comonomer content is sufficient to reach a conductivity of 0.3 × 10−4 S cm−1 at 25 °C. The Li+ transference number is 0.6, indicating that the comonomer units not only limit the crystallinity but also weaken the strength of the Li+ coordination to the polymer. The resulting solid polymer electrolyte is effective in an all-solid LFP|Li-metal battery operating at 25 °C, demonstrating that statistical copolymerization is an efficient tool for polymer electrolyte design.
BaCuSiTe3 was prepared from the elements in a solid-state reaction at 973
K, followed by slow cooling to room temperature. This telluride adopts
a new, hitherto unknown structure type, crystallizing in the noncentrosymmetric
space group Pc with a = 7.5824(1)
Å, b = 8.8440(1) Å, c =
13.1289(2) Å, β = 122.022(1)°, and V = 746.45(2) Å3 (Z = 4). The structure consists of a complex network
of two-dimensionally connected CuTe4 tetrahedra and ethane-like
Si2Te6 units with a Si–Si bond. This
semiconducting material has an optical band gap of 1.65 eV and a low
thermal conductivity of 0.50 W m–1 K–1 at 300 K. Calculations of its optical properties revealed a moderate
birefringence of 0.23 and a second-order harmonic generation response
of d
eff = 3.4 pm V–1 in the static limit.
CoS2/NC@1T MoS2 synthesized by a one-step hydrothermal method forms a unique hierarchical configuration with simultaneous internal and external modifications. A lithium–sulfur battery with a CoS2/NC@1T MoS2-PP separator shows superior cycling performance.
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