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Background: World health organization estimates that 25 million low birth weight (LBW) babies are born annually worldwide and 95% occur in developing countries. Low birth weight is a major public health problem of Bangladesh. So an attempt was made to study the incidence of low birth weight (<2.5kg) and also the associated risk factors of low birth weight among the new born babies born to Dhaka Medical College Hospital.Aims: To determine the Prevalence of low weight among the babies born and to determine the relationship of low birth weight with maternal factor like maternal weight, height, gestational period, antenatal checkup, heavy physical work during pregnancy, hypertension, age of the mother and parity, in Obs. & Gynae Department, DMCH.Method: This descriptive cross sectional study was done in Gynecology and Obstetrics Department of Dhaka Medical College Hospital. Five hundred (500) samples were selected for the study. The study was done from 1st January 2006 to 31 December 2006. Data processing and questionnaire are processed manually using scientific calculator and by computer using SPSS programmers version-16. All abortions, still born, gross congenital abnormalities were excluded from this study. The cut off point used for low birth weight is 2.5 kg.Results: A total of 500 women were interviewed. The incidence of low birth were found 21.6%. Younger than 20 yrs (31.25%) and more than 40 years (35.71%) mother delivered more low birth weight babies. The primigravida and multigravida (>4 parity) showed more low birth weight babies. Women from low socioeconomic condition produced significantly larger number of low birth weight babies as well as short stature. Low maternal height, less educated, illiterate, manual worker mother delivered more low birth weight babies. Preterm birth comprises larger number of low birth weight (LBW 35%). Low height of new born babies also associated with low birth weight. Female babies were higher than the male babies. Preterm babies were lighter (LBW) than the full term babies.Conclusion: The study finds out the incidence of low birth babies, the figure close to the developing countries. The study revealed that maternal age, gestational age, parity, socioeconomic status, maternal weight and disease condition have strong relations with birth weight of babies. Occupation and antenatal check up also affects birth weight of babies.J Shaheed Suhrawardy Med Coll, June 2018, Vol.10(1); 16-22

Background: In obstetric management fetal weight estimation is an important consideration when planning the mode of delivery in our day to day practice. In Bangladesh low birth weight is a major public health problem & incidence is 38% - 58%. Neonatal mortality and morbidity also yet high. So accurate antenatal estimation of fetal weight is a good way to detect macrosomia or small for date baby. Thus to improve the pregnancy outcome and neonatal outcome decreasing various chance of neonatal mortality and morbidity antenatal fetal weight prediction is an invaluable parameter in some situation where to identify the at risk pregnancy for low birth weight become necessary. Reliable method for prenatal estimation of fetal weight two modalities have got popularity - Clinical estimation and another one is ultrasonic estimation. This study was designed to determine the accuracy of clinical versus ultrasound estimated fetal weight detecting the discrepancy with actual birth weight at third trimester. So that we can verify more reliable and accurate method. Objectives: To find out more accurate and reliable modality of fetal weight estimation in antenatal period during obstetric management planning. To compare clinical versus ultrasound estimated fetal weight & to determine discrepancy of both variable with actual birth weight. Method: This prospective, cross sectional analytical study was carried out in Dhaka Medical College Hospital from January 2006 to December 2006. By purposive sampling 100 pregnant women fulfilling inclusion criteria were included in my study in third trimester (29wks-40wks). In clinical weight estimation procedure SFH (Symphysio Fundal Height) was measured in centimeter. On pervaginal finding whether vertex below or above the ischial spine was determined. By Johnson’s formula fetal weight in grams was estimated. Then by ultrasound scan different biometric measurements were taken and finally by Hadlock’s formula fetal weight was estimated. Eventually actual birth weight was taken after birth by Globe Brand weighing machine. Accuracy of both modalities were compared and which one was more reliable predictor was determined by statistical analysis. Results: After data collection were analyzed by computer based software (SPSS). There was gradual and positive relationship between symphysiofundal height and estimated birth weight. Discrepancy between clinical and actual birth weight at third trimester was statistically significant – Paired Student’s ‘t’ test was done where p value was <0.001. Whereas discrepancy between sonographically estimated fetal weight with actual birth weight was not statistically significant (by paired ‘t’ test where p value was >0.05). That implies discrepancy between ultrasound estimated fetal weight and actual birth weight was significantly less than that of clinically estimated fetal weight. 14% clinically and 46% sonographically estimated fetal weight were observed within £ 5% of actual birth weight. 31% clinical and 42% sonographically estimates observed within 6% to 10% of actual birth weight and 55% clinical and 12% sonographically estimate were >10% of actual birth weight. That is about 88% sonographical versus 45% clinical estimates were within 10% of actual birth weight. Conclusion: There is no doubt about importance of fetal weight in many obstetric situations. Clinical decisions at times depends on fetal weight. Whether to use oxytocin, to use forceps or vacuum for delivery or extend of trial or ended by Caesarian section immediately or no scope of trial to be largely depend on fetal size and weight. So more accurate modality for antenatal fetal weight estimation has paramount importance. In my study sonographically estimated weight have more accuracy than that of clinical estimate in predicting actual birth weight. Sonographically estimated fetal weight is more reliable, accurate and reproducible rather than other modality. J Shaheed Suhrawardy Med Coll, June 2019, Vol.11(1); 32-38

Background: Adjunctive therapies to have a baby and widespread perception is that dietary supplementation such as myo-inositol are associated with only benefit, not with harm in case of PCOS women. The use of 2×1000mg myo-inositol +2×200microgram folic acid per day is a safe and promising tool in the effective improvement of symptoms and infertility for patients with a PCOS. Objectives: To evaluate the effectiveness and safety of oral supplementation of inositol for reproductive outcomes among subfertile women with PCOS who are trying to conceive. Materials and methods: Using questionnaire an observational study was performed in ShSMCH of outdoor infertility clinic and routine clinical practiced. In this observational study Thirtyfive PCOS women of childbearing age with oligo or amenorrhea were enrolled in the study. Ovulatory disorder due to PCOS was apparently the only cause of infertility; no tubal defect or deficiency of male semen parameters was found. Myo-inositol combined with folic acid 2g twice a day was administered continuously. During an observation period of 6 months from July,2018 to December, 2018, ovulatory activity was monitored with ultrasound scan and hormone profile and the number of spontaneous menstrual cycles and eventually pregnancies were assessed. Results: Twenty eight out of 35 (80%) patients restored their spontaneous menstrual cycle during treatment. A total of 10 singleton pregnancies (28.5% of patients) were obtained. Nine clinical pregnancies were assessed with fetal heart beat at USG scan. One pregnancies evolved in spontaneous abortion. Conclusion: Myo-inositol is a simple and safe treatment that is capable of restoring spontaneous ovarian activity and consequently fertility in most patients with PCOS. This therapy did not cause multiple pregnancy. J Shaheed Suhrawardy Med Coll, December 2019, Vol.11(2); 115-118

Background: Preeclampsia (PE) is a pregnancy related condition leading to significant mortality and morbidity. A number of renal changes are seen in preeclampsia. Objectives: This study was designed to determine the association of calcium to creatinine ratio in a spot sample of urine with preeclampsia. Methodology: This cross-sectional comparative study was conducted in the Obstetrics & Gynaecology department of Dhaka Medical College, Dhaka, Bangladesh. Pregnant women with preeclampsia without complication and women with normal pregnancy without complications were selected for the study. Calcium, creatinine, Protein and calcium to creatinine ratio was measured in a spot urine sample of all these 150 subjects. Blood was also collected from all the cases for measurement of serum calcium, creatinine and uric acid. Results: A total of 150 pregnant women, 75 with preeclampsia without complication and 75 with normal pregnancy without complications were selected for the study. Significant difference between PE and normal group was observed in case of mean serum calcium and uric acid concentration but mean serum creatinine did not vary significantly. Urinary creatinine concentration did not show any significant difference. But mean urinary calcium concentration in spot sample of urine was significantly lower in preeclampsia than normal pregnant woman (3.45 ± 2.61 mg/dl vs 7.39 ± 2.80 mg/dl, p< 0.001). Similarly mean calcium to creatinine ratio in spot sample of urine was significantly lower in the pre-eclampsia than normal group (0.06 ± 0.05 vs 0.13 ± 0.06, p<0.001). Positive correlation was observed between urinary calcium/creatinine ratio and urinary calcium (r=+0.68, p<0.001) but negative correlation (r = -0.39, p<0.001) noted between urinary calcium/creatinine and urinary protein. Conclusion: Spot urinary calcium and creatinine ratio decreases in preeclampsia. So spot urinary calcium and creatinine ratio can be regarded as a predictor for preeclampsia.