Background: Routine medical checkups are one strategy for detecting and treating noncommunicable diseases early. Despite the effort to prevent and control noncommunicable diseases in Ethiopia, the prevalence of the problem is significantly increasing. The aim of this study was to assess the uptake of routine medical checkups for common noncommunicable diseases and associated factors among healthcare professionals in Addis Ababa, Ethiopia, in 2022. Methods: A facility-based cross-sectional study was conducted, enroling 422 healthcare providers in Addis Ababa. A simple random sampling method was used to select study participants. Data entry was made using Epi-data and exported to STATA for further analysis. A binary logistic regression model was used to determine predictors of routine medical checkups. In the multivariable analysis, the adjusted odds ratio along with a 95% confidence interval were determined. Explanatory variables whose p value less than 0.05 were selected as significant factors. Results: The overall uptake of routine medical checkups for common noncommunicable disease was 35.3% (95% CI: 32.34–38.26). Moreover, being married [adjusted odds ratio (AOR)=2.60, 95% CI=1.42–4.76], income level less than 7071 (AOR=3.05, 95% CI=1.23–10.05), absence of chronic medical disease (AOR=0.40, 95% CI=0.18–0.88), good provider commitment (AOR=4.80, 95% CI=1.63–14.05), drinking alcohol (AOR=0.35, 95% CI=0.19–0.65), and poor perception of health status (AOR=2.1, 95% CI=1.01–4.44) were the significant factors. Conclusion: The uptake of routine medical checkups was found to be low, owing to marital status, level of income, perception of health status, drinking alcohol, the absence of chronic medical conditions, and the availability of committed providers, which needs intervention. We recommend using committed providers for noncommunicable diseases and considering fee waivers for healthcare professionals to increase uptake of routine medical checkups.