IntroductionOtomycosis is a subacute or chronic fungal infection of the external auditory canal with some complications involving the middle ear.There are several factors that play important roles in otomycosis infection, such as humidity, moisture, high temperature, the entrance of water into the ear during swimming or sweat secretions, increased use of topical antibiotics, weak immune function, and cleaning of ear wax (1).Molds and yeasts are common in the auditory canals of otomycosis patients. The predominance of thermophile Aspergillus and Candida species are related to the inflammatory processes of the ear. The molds mostly isolated from the ear are Aspergillus niger, Aspergillus fumigatus, Aspergillus flavus, Aspergillus nidulans, Aspergillus terreus, Mucor species, and Penicillium species (2).Otomycosis has a worldwide distribution. It is estimated that approximately 25% of the total cases of ear infections are due to fungi, and the disease was more prevalent in warm and humid climates. Otomycosis infection is prevalent in Brazil and constitutes about 30% of the mycotic diseases of the external auditory canal (3). Otomycosis is also frequently seen in Turkey (4). In Egypt, there has been no recent survey on otomycosis epidemiology, risk factors, and complications. The last study recorded was that of Hammad (5) on otomycosis in the El-Minia University hospitals, where he locally diagnosed otomycosis through direct examination by otoscope, and collected 250 otomycotic fungal samples over a 12-month period without any detailed identification studies or new approaches in the treatment with natural products. Materials and methods Study groupMycological analysis was carried out on debris, scrapings, or exudate samples from the auditory canals of 110 patients clinically diagnosed to have otomycosis infection.