Extraction solvent-dependent antioxidant activities and cancer cell growth inhibitory effects of Scutellaria baicalensis extracts

No abstract

This study was conducted to examine the physicochemical properties and antioxidant activities of spray-dried (SD) powders using different cyclodextrin and maltodextrin ratios of safflower extract. The extraction yield of SD powders was 68.02-87.68%. The moisture content of 10% maltodextrin spray-dried powder (MD10) was higher than that of the other powders investigated. The color values L, a, and b of SD powders were higher than those of freeze-dried (FD) powder. The particle size increased as the wall material increased. Scanning electron microscope (SEM) images showed that the SD powders were spherical. The water absorption index and water solubility index of the SD powders were 0.55-0.61 and 90.67-96.67%, respectively. The decomposition temperature of SD powders was 283℃. The concentration of the phenolic compounds of MD10 (1.07 g/100 g) was higher than those of the SD powders (0.20-1.06 g/100 g). The DPPH and ABTS radical scavenging activities of MD10 at 1,000 μg/mL were 13.40 and 24.10%, respectively. The FRAP activity of SD powders from 100 to 1,000 μg/mL was 16.70 to 191.57 μM, respectively. The superoxide radical scavenging activity of MD10 (85.37%) was superior to those of other SD powders. This study suggests that SD powders with safflower extract have enhanced storage stability and may be useful as functional processing materials.