This study aims to obtain cellulase enzymes from selected molds for microcrystalline cellulose preparation from ????-cellulose of kapok cortex. Alpha-cellulose was obtained by biodelignification, and the purified cellulase was obtained from the selected mold. The Microcrystalline cellulose obtained from enzymatic hydrolysis was then identified FTIR and DSC, followed by characterization of microcrystalline cellulose, Particle Size and Distribution Analysis (PSA), and Scanning Electron Microscope-Energy Dispersive X-ray (SEM-EDX), Loss on drying, pH, bulk density, tapped density, and flow rate. Biodelignification produced 14.88% ????-cellulose, Penicillium sp. the selected mold had the highest cellulase activity, with a cellulolytic index of 4.83. FTIR identification was similar to Avicel PH 101 with a melting point of 244.580°C. Loss on drying was 3.74%, pH was 7.0, particle size ranged from 13.06 to 196.79 ????m, bulk density and tapped density were 0.11 g/cm3 and 0.23 g/cm3, respectively flow rate character is quite good. SEM-EDX was showed that the morphological shape of the microcrystalline cellulose of the kapok cortex is elongated. Microcrystalline cellulose has shown a quite similar in character and can be furthered.

Powder characteristics are very important to consider in the tablet manufacturing process because they can affect the characteristics of the resulting tablets. This study aims to determine the characteristics of microcrystalline cellulose powder isolated from soursop leaves. This research method includes preparation of soursop leaves raw material, isolation of α-cellulose using 17.5% NaOH solution with 3.5% nitric acid (containing 20 mg sodium nitrite), manufacture of microcrystalline cellulose using 1 M HCl solution, and characterization of microcrystalline cellulose including quality checks. powder (organoleptic, identification, solubility), and pH testing. The results showed that the yield of microcrystalline cellulose (MCCDSr) was 96.59% against α-cellulose. The results of the characterization of microcrystalline cellulose powder including organoleptic, identification, solubility, melting point, and pH showed similar characteristics with Avicel® PH 101 as a comparison. Based on the research that has been done, the characteristics of microcrystalline cellulose powder from soursop leaves are similar to Avicel® PH 101.