The novel coronavirus disease (COVID-19) has caused a pandemic that has disrupted supply chains globally. This black swan event is challenging industries from all sectors of the economy including those industries directly needed to produce items that safeguard us from the disease itself, especially personal protection equipment (N95 masks, face shields) and much needed consumables associated with testing and vaccine delivery (swabs, vials and viral transfer medium). Digital manufacturing, especially 3D printing, has been promulgated as an important approach for the rapid development of new products as well as a replacement manufacturing technique for many traditional manufacturing methods, including injection molding, when supply chains are disrupted. Herein we report the use of Digital Light Synthesis (DLS) for the design and large-scale deployment of nasopharyngeal (NP) swabs for testing of coronavirus SARS-CoV-2 infections in humans. NP swabs have been one of society's essential products hardest hit by the supply chain disruptions caused by COVID-19. A latticed tip NP swab was designed and fabricated by DLS from a liquid resin previously developed and approved for use to make dental night guard devices. These latticed NP swabs demonstrated non-inferiority in a human clinical study of patients suspected of being infected with SARS-CoV-2.
This study aims to examine the subtypes of directives and their realization patterns in Taiwanese Southern Min (TSM). The data were drawn from a play script corpus published in the 20th century. Nine directive subtypes were identified: advice, begging, invitation, order, offer, request, suggestion, urge, and warning. The realization patterns were analyzed in terms of the main components in the directives: alerter, discourse marker, politeness marker, subject, modal expression, verb phrase, and utterance final particle. The analysis reveals a number of features: (1) Alerters mainly take the form of an address term; (2) Utterance-initial discourse markers are mainly realized by tan
‘now’; (3) The subject is either hearer-dominated or speaker- and hearer-dominated, with the latter expressing solidarity in casual situations; (4) the politeness marker chhiáⁿ tends to take an overt subject; (5) The modal verb tio̍h accounts for the majority of subtypes; (6) The dominant verb types include dynamic, stative, uttering, and ingesting verbs; (7) Complex verb constructions mainly include directional verbs, disposal markers, and benefactive verbs; (8) Directional verbs are pervasive across all directives. A metaphorical transfer is operative in the use of directional verbs. Those marking an action toward the speaker (e.g., lâi ‘come’) are strongly associated with a positive attitude, while those expressing movement away from the speaker (e.g., khì ‘go’) are highly connected to an adversative mood. The omnipresence of [lâi V] suggests that it has been conventionalized as a default bundle to express politeness.
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