Laplace’s law relates the pressure inside a hollow sphere with its radius and the tension in its walls. A theoretical model implementing Laplace’s law in the eye globe is presented. The physical model may help to explain certain aspects in glaucomatous disk damage such as higher susceptibility of myopic eyes to glaucomatous damage and a possible explanation for glaucoma nerve head damage in low tension glaucoma.
An IOL type that is appropriate for implantation in the ciliary sulcus is a viable option for correcting pseudophakic refractive error using the piggyback technique.
This patient was a 36-year-old female, the sister of case 1. She also has Morquio syndrome, with severe dwarfism. She is known to have had corneal clouding in both eyes for many years.A raised IOP in both eyes was found five years ago, and since then she has been treated with 1% epinephrine and 0-5% timolol meleate twice daily. She was referred to us for further evaluation of her ocular status.On examination her height was found to be 75 cm. She had kyphoscoliosis, a short neck, pectus carinatum, and a cardiac murmur due to aortic regurgitation.The visual acuity was 20/100 in both eyes. The IOP was 31 mmHg without treatment. Both corneas had hypoaesthesia and diffuse stromal clouding, containing numerous small dust-like opacities. The anterior chamber was deep, and gonioscopy revealed an open angle, but the details could not be examined owing to corneal opacity. The lens was clear in both eyes, and fundus examination was impeded by a hazy view. The axial length was 22-0 mm in the right eye and 21-1 mm in the left. No specific visual field defects other than generalised constriction of field were found.The ERG recordings showed normal photopic and scotopic responses, and the VEP revealed normal conduction in the optic pathway. Colour vision was normal.
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