Purpose
Reduce expense and increase accessibility of MRI by eliminating pulsed field (B0) gradient hardware.
Methods
A radiofrequency imaging method is described that enables spatial encoding without B0 gradients. This method, herein referred to as frequency‐modulated Rabi‐encoded echoes (FREE), utilizes adiabatic full passage pulses and a gradient in the RF field (B1) to produce spatially dependent phase modulation, equivalent to conventional phase encoding. In this work, Cartesian phase encoding was accomplished using FREE in a multi‐shot double spin‐echo sequence. Theoretical analysis and computer simulations investigated the influence of resonance offset and B1‐gradient steepness and magnitude on reconstruction quality, which limit other radiofrequency imaging methodologies. Experimentally, FREE was compared to conventional phase‐encoded MRI on human visual cortex using a simple surface transceiver coil.
Results
Image distortions occurred in FREE when using nonlinear B1 fields where the phase dependence becomes nonlinear, but with minimal change in signal intensity. Resonance offset effects were minimal for Larmor frequencies within the adiabatic full‐passage pulse bandwidth.
Conclusion
For the first time, FREE enabled slice‐selective 2D imaging of the human brain without a B0 gradient in the y‐direction. FREE achieved high resolution in regions where the B1 gradient was steepest, whereas images were distorted in regions where nonlinearity in the B1 gradient was significant. Given that FREE experiences no significant signal loss due to B1 nonlinearities and resonance offset, image distortions shown in this work might be corrected in the future based on B1 and B0 maps.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.