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Posters 284 monitoring and hypothermia therapy in asphyxiated neonates, most level 2 units do not currently offer CFM, and a significant minority of tertiary level UK neonatal units do not currently offer brain monitoring or hypothermia therapy. CORRELATION BETWEEN AMPLITUDE-INTEGRATED EEG (AEEG) AND GENERAL MOVEMENTS (GMS) IN PRETERM INFANTSA. Scoppa, M.G. De Luca, M. Di Biase, M.G. Di Stefano, L. Orfeo NICU and PICU, G. Rummo, Benevento, ItalySince today the correlation between background cerebral electrical activity at aEEG and brain injury in preterm is unknown. The aim of the present study is to correlate the background activity at aEEG to the patterns of General Movements at writhing age and to avaluate if aEEG is predictive for cerebral palsy.Methods: 17 preterms between 27 and 31 weeks of gestational age with normal head ultrasound were included. The aEEG were recorded during the first 24 hours of life for 60 minutes. The averaged signals were analysed off-line. Background activity was classified into three patterns categories: discontinous low-voltage pattern (minimal amplitude < 3µV), discontinous high voltage pattern (minimal amplitude between 3 and 5 µV ) and continous pattern. General movements were performed during the first 24 hours of life and weekly during writhing age.Results: A background low-voltage pattern correlates positively with Cramped Synchronized General Movements (R: 0.74, p = 0.004), on the other way a high voltage pattern and a continous pattern correlates with normal General Movements (R: 0.67, p=0.006). Conclusions:A discontinous low voltage pattern at aEEG in preterm could be expression of cerebral injury and/or altered maturation. In fact this aEEG pattern highly correlates with pathological Cramped Synchronized General Movements leading to the hypotesis of a similar strong correlation between discontinous low voltage pattern and cerebral palsy in this range of gestational age. NEUROSONOGRAPHY AND HEMOSTASIS DATA IN PREMATURE NEWBORNS WITH HYPOXIC-ISCHEMIC ENCEPHALOPATHY B. Burov Private Clinic GMS, Tashkent, UzbekistanAim: Hypoxic -ischemic damages of the brain in preterm newborns is the significant current problem of neоnatology. Materials and methods:140 newborns of 28-36 weeks gestation with 820-2650 gr. have been investigated. The 1st group included children with intra -and -periventricular I, II, III degree bleedings. The 2nd group included patients with I, II, III degree hypoxic -ischemic damages of CNS. The 3rd group included so called *healphy* children without clinical and ultrasound signs of brain damage. Paraclinical methods included haemostasis condition on 1st, 3rd, 5th, 7th days of life. Being correlated to disturbances of hemo-liguorodynamic data and ventriculometry.Results: On the 3rd day of life 5,1% decrease of fibrinogen count in blood serum have been noted. Increase of thrombocites (10.4%) and simultaneous decrease of APTT (7.3%) in 1st group children in comparison to control group have been revealed. In the 2nd group the spread and duration of celebral isc...