In recent years, some methods of sentiment analysis have been developed for the health domain; however, the diabetes domain has not been explored yet. In addition, there is a lack of approaches that analyze the positive or negative orientation of each aspect contained in a document (a review, a piece of news, and a tweet, among others). Based on this understanding, we propose an aspect-level sentiment analysis method based on ontologies in the diabetes domain. The sentiment of the aspects is calculated by considering the words around the aspect which are obtained through N-gram methods (N-gram after, N-gram before, and N-gram around). To evaluate the effectiveness of our method, we obtained a corpus from Twitter, which has been manually labelled at aspect level as positive, negative, or neutral. The experimental results show that the best result was obtained through the N-gram around method with a precision of 81.93%, a recall of 81.13%, and an F-measure of 81.24%.
BackgroundIntegration and analysis of phenotype data from humans and model organisms is a key challenge in building our understanding of normal biology and pathophysiology. However, the range of phenotypes and anatomical details being captured in clinical and model organism databases presents complex problems when attempting to match classes across species and across phenotypes as diverse as behaviour and neoplasia. We have previously developed PhenomeNET, a system for disease gene prioritization that includes as one of its components an ontology designed to integrate phenotype ontologies. While not applicable to matching arbitrary ontologies, PhenomeNET can be used to identify related phenotypes in different species, including human, mouse, zebrafish, nematode worm, fruit fly, and yeast.ResultsHere, we apply the PhenomeNET to identify related classes from two phenotype and two disease ontologies using automated reasoning. We demonstrate that we can identify a large number of mappings, some of which require automated reasoning and cannot easily be identified through lexical approaches alone. Combining automated reasoning with lexical matching further improves results in aligning ontologies.ConclusionsPhenomeNET can be used to align and integrate phenotype ontologies. The results can be utilized for biomedical analyses in which phenomena observed in model organisms are used to identify causative genes and mutations underlying human disease.Electronic supplementary materialThe online version of this article (doi:10.1186/s13326-017-0167-4) contains supplementary material, which is available to authorized users.
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