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ABSTRACT. The anthelmintic efficacy of milbemycin oxime against dog whipworm, Trichuris vulpis, was evaluated. A total of 21 T. vulpis positive dogs were divided into 3 groups, one (5 dogs) for control and the other two (8 dogs each) for anthelmintic treatment with oral administration of milbemycin oxime. Milbemycin oxime showed mean efficacies of 96.0% and 98.6%, at doses of 0.5 mg and 1.0 mg base/kg of body weight, respectively. Milbemycin oxime is generally used as a prophylactic drug for D. immitis at a dose of 0.25-0.5 mg base/kg. If the highest dose (0.5 mg base/kg) was chosen for a prophylactic treatment of D. immitis, it is also effective against T. vulpis as well as other intestinal helminths [6], e.g., T. canis and A. caninum. Milbemycin oxime also seems to be a useful and safety drug for controlling not only heartworms but also common intestinal nematodes in dogs.ACKNOWLEDGEMENT. The authors thank Dr. K. K. Amoako for his critical reading of the manuscript.