This paper describes a translational application of the space-time distribution pattern of LF epidemics, 2008-2012 reported in Liberia, on which a predictive model was developed. We proposed a computationally feasible two-stage space-time permutation approach to estimate the time-trend parameters and conduct predictive inference on LF in Liberia.

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Background: Pregnant women in malaria-endemic areas are at high risk of Plasmodium falciparum infection and its complications. This study investigated the impact of asymptomatic P. falciparum on haematological parameters of pregnant women at first antenatal visit in south-western Nigeria.Methods: Hospital-based cross-sectional evaluation of 130 asymptomatic pregnant women was conducted. Plasmodium infection was diagnosed using Giemsa-stained blood smear microscopy and rapid diagnostic test, while haemoglobin levels (Hb), Packed Cell Volume (PCV), white blood cells (WBC) count, red blood cell (RBC), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH) and mean corpuscular haemoglobin concentration (MCHC) were determined using semi-automated haematology analyser.Results: Multigravid pregnant women presented more during their second trimester. Overall malaria prevalence in the sampled population was 14.6%. Prevalence of malaria parasitaemia was highest (68.4%) in the second trimester. P. falciparum infected pregnant women had significantly lower mean values of packed cell volume (PCV), haematocrit (Hb), and total white blood cell (WBC) compared to non-infected  individuals  (t = -4.07, p= 0.001; t = 3.30, p = <0.001; t = -2.77, p <0.001).Conclusion: There is asymptomatic P. falciparum infection in the study area and this may form a reservoir for transmission. Pregnant women infected with malaria parasites exhibited important changes in haematocrit level, haemoglobin concentration, and total white blood cells. Use of anti-malaria therapy and insecticide-treated bed net would result in greater haematological benefits.

Aim:  To explore the risk perception of Ebola virus disease (EVD) among mortuary workers in Nigeria. Study Design:  A qualitative research approach method, using Focus Group Discussions (FGDs), conducted among 36 mortuary workers in Ibadan. Place and Duration of Study: This study was conducted between October and November 2014 in Ibadan, Oyo state, Nigeria. Methodology: A structured moderating approach with a non-directive style was developed. A Focus Group Discussion (FGD) guide was used to explore participants’ ideas and opinions. The FGD guide consisted of five sections. Each section was framed to probe into the following issues:                  (1). Knowledge of EVD (2). Participant’s attitude to EVD (3). Adherence to infection control practices (4). Risk perception of EVD; and (5). Behavioural predisposition to the risk of mortuary-related infections. A total of six FGD sessions were conducted among 36 mortuary attendants, drawn from two government and four private health facilities in Ibadan. Six participants made up each focus group and one focus group discussion was conducted at a time in the respective health facilities. Results: The qualitative exploration of mortuary workers revealed gaps in the knowledge of workers with regards to EVD, the high-risk perception of mortuary workers to Ebola virus disease and the unavailability of PPE in conducting autopsies and daily operations. In addition, a poor attitude to convalescent individuals and certain harmful behavioural practices in the morgue were revealed as key findings. Conclusion: Efforts at bridging the knowledge gaps concerning EVD among mortuary workers should be sustained, despite the decline in Ebola outbreaks. It is also recommended that standard precautions should be followed when handling corpses due to the risk of infection.