Primary intracranial malignant melanoma is a rare disease, and the imaging findings usually mimic meningioma. Diagnosis is based on histology. Here, we report a case of primary intracranial malignant melanoma in a Chinese patient. A 27-year-old man presented with a 1-month history of headache. Magnetic resonance imaging findings resembled features of a meningioma. Craniotomy with tumour excision was done and confirmed to be S100 and human melanoma black 45-negative primary intracranial malignant melanoma. There was no extracranial involvement. The 9-month follow up was reported. To our knowledge, this is the first reported S100 and human melanoma black 45-negative primary intracranial amelanotic malignant melanoma.

Transcranial magnetic stimulation is an non-invasive method of neuromodulation. It uses magnetic field to induce generation of current for cortical stimulation. It can modulate the altered equilibrium in cortical excitability by magnetic field. Though it is famous for its application in treating psychiatric diseases, it has many other applications. Since its introduction in 1985, it has been used to check the integrity of motor pathway. With more understanding of the technique, it has been started to be used to check the integrity of other brain connections like speech and vision. Due to its ability of neuromodulation, it has also been used in cortical mapping in neurosurgery and neurological function rehabilitation.

Sinovenous stenosis is suggested to be related to benign intracranial hypertension. Endovascular treatment is effective in improving vision by overcoming these stenoses. We reported a case of benign intracranial hypertension with underlying right sigmoid sinus stenosis and left hypoplastic transverse sinus. Angioplasty for the right sigmoid sinus stenosis was carried out and the patient's vision improved. However, the intracranial pressure was still high approximately 1 year after angioplasty.