During wound healing, oxygen availability and the anti-inflammatory microenvironment play an important role in the formation of new tissue. However, providing continuous and controllable oxygen around the injured tissue while inhibiting inflammation and realizing the synergistic effect of oxygen supply and anti-inflammation is still a major problem affecting the regeneration and repair of wound tissue. Inspired by skin wound pathology and the inflammatory microenvironment, a photothermal response-assisted strategy was developed in this study. We prepared a composite hydrogel system of polydopamine-hyaluronic acid (PDA-HA) hydrogel-loaded calcium peroxide-indocyanine green combined with lauric acid and manganese dioxide (CaO2-ICG@LA@MnO2) nanoparticles that showed excellent photothermal performance under near-infrared (NIR) irradiation and realized the on-off release of oxygen and reactive oxygen species (ROS). Controllable and sustainable oxygen release can promote the regeneration and repair of damaged tissue, and the generated ROS can effectively inhibit the outbreak of inflammation at the initial stage of wound healing. We believe that the system we have developed can be used in a new approach for treating chronic wounds.
Compared
with conventional transparent conductive indium tin oxide
(ITO) films, poly(3,4-ethylenedioxythiophene):poly (styrenesulfonic
acid) (PEDOT:PSS) as a conductive polymer material has been diffusely
applied in organic optoelectronic devices. However, its optoelectrical
properties need to be further improved. Therefore, a simple and universal
approach with introducing ITO nanoparticles (NPs) was proposed to
improve the optoelectrical properties of PEDOT:PSS thin films. The
results show that the vertical conductivity (σDC⊥) and average transmittance (from 300 to 1200 nm) of PEDOT:PSS films
were enhanced about 26.8 and 6.3%, respectively. Crystalline silicon
(c-Si)/organic heterojunction solar cells (HSCs) with PEDOT:PSS/ITO
NP hybrid films were fabricated and performances led to further improvement.
The spatial distributions of relative electrical field intensity and
the carrier generation rate of the HSCs under the standard AM 1.5
G condition were simulated, which were in good agreement with the
experimental conclusions.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.