Eggshell (ES) is a waste material that cannot be consumed with low economic value. ES mainly contains calcium carbonate (CaCO3) and an organic matrix in the form of proteins, glycoproteins, and proteoglycans. Meanwhile, the eggshell membrane (ESM) contains osteopontin collagen, fibronectin, keratin, histones, avian beta defensins, ovocalyxin-36, apolipoproteins, protocadherin, chondroitin sulfate, ovotransferrin, hyaluronic acid, and sialic acid as well as various amino acids. Recently, ES has been widely used in industry, agriculture, food, and medical fields. The potential of ES in the medical field is interesting to discuss, especially in relation to tissue repair. Efforts to reduce the prevalence of wounds that generally originate from acute wounds but become chronic due to various factors that are neglected in their management. In particular, this review will describe the benefits of ES content in repairing body tissues. ES-derived active ingredients such as CaCO3, brushite, and hydroxyapatite exhibit osteoconductive properties that promote bone regeneration. Calcium ions can increase insulin and leptin sensitivity in the liver and can induce repair of acute kidney injury. Meanwhile, ESM contributes positively to neural tissue repair and plays an important role in wound healing, response to external stimuli, defense response, inflammatory response, cell-substrate adhesion, promoting cell growth, migration, differentiation, and tissue remodeling.
The classic standard criteria to diagnose osteoarthritis (OA) of the knee is the conventional radiological imaging. Ultrasonography could assess the osteoarthritis early and show invisible joint structures in osteoarthritis. This study aimed to compare the cartilage changes of trochlear femur and osteophytes (femur and tibia) through ultrasound examination with the radiological imaging in stages to Kellgren-Lawrence (KL) classification. This is an observational study using cross-sectional design, involved 33 patients with knee OA who underwent conventional photo examination and ultrasonography at dr. Wahidin Sudirohusodo Makassar Hospital in the period of June - August 2019. Spearman's test showed that there is a significant correlation between the stage of OA by KL and the stage of femoral trochlear cartilage damage (p 0.001) with strong correlation (r 0.828). Significant correlation is also between the stage of OA and the stage of osteophytes on the femur-lateral condylus both medial and lateral sides (p 0.001) with strong correlation (r 0.823; 0.79; 0.816, and 0.818). It concluded that the higher grade of femoral trochlear cartilage damage will result in the higher the stage of OA. The higher grade of osteophytes in knee joints will also result in the higher the stage of OA.
Limfadenopati dapat disebabkan oleh berbagai kondisi mulai dari keganasan, infeksi, autoimun, dan iatrogenik. Limfadenopati pada usia anak dan dewasa yang ukurannya tidak bertambah besar dalam kurun waktu kurang dari dua minggu atau lebih dari 12 bulan tidak bersifat neoplastik. Penelitian ini bertujuan mengetahui kesesuaian gambaran CT Scan leher dengan hasil biopsi aspirasi jarum halus (BAJAH) untuk membedakan limfadenopati leher yang jinak dan ganas. Penelitian ini dilaksanakan di Departemen Radiologi RS. Dr. Wahidin Sudirohusodo dan RS Universitas Hasanuddin Makassar mulai bulan Desember 2017 sampai Mei 2018. Sampel sebanyak 61 orang dengan rentang usia 4 - 82 tahun. Metode yang digunakan adalah observasional analitik dengan pendekatan cross sectional. Hasil penelitian menunjukkan gambaran keganasan limfadenopati leher pada CT Scan yang sesuai dengan BAJAH yaitu penyebaran ekstrakapsular, nekrosis sentral, bentuk bulat/lobulated dan margin irregular, sedangkan kalsifikasi dan ukuran tidak sesuai. Gambaran CT Scan limfadenopati leher yang jinak sesuai dengan hasil BAJAH yaitu tidak ada penyebaran ekstrakapsular, tidak ada nekrosis sentral, bentuk oval dan margin regular, sedangkan kalsifikasi dan ukuran tidak sesuai. Lymphadenopathy can be caused by various conditions that were malignancy, infection, autoimmunity, and iatrogenic. In adults and children, lymphadenopathy whose duration is less than two weeks or more than 12 months but its size does not increase, that is not a neoplastic. The study aims to determine the relationship between CT Scan of neck image and the result of fine needle aspiration biopsy (FNAB) in distinguishing benign and malignant cervical lymphadenopathies. The research was conducted in Radiology Department of Dr. Wahidin Sudirohusodo and Universitas Hasanuddin Hospital Makassar from December to May 2018. The sample were 61 people aged form 4 – 82 years old. The observational analytic with cross sectional analytic were used in this study. The result revealed that image of malignant lymphadenopathies in CT Scan of neck were significantly related with FNAB results; extracapsular spread; central necrosis, lobulated or rounded forms with irregular margin, while calcification and size were not related. The image of benign lymphadenopathies in CT Scan of neck was related with FNAB results; no extracapsular spread, no central necrosis, oval formed with regular margin, while calcification and size were not related.
Tujuan: Mengetahui korelasi plak, ketebalan tunika intima-media arteri karotis berdasarkan ultrasonografi dan skor kalsium total dengan derajat stenosis arteri koroner berdasarkan MSCT-scan kardiak pada pasien dislipidemia. Metode: Cross-sectional, dilakukan di instalasi radiologi sentral RSUP dr. Wahidin Sudirohusodo, Makassar mulai bulan Juli 2018 sampai Juli 2019. Sampel sebanyak 32 orang dengan usia >18 tahun dan memiliki riwayat dislipidemia. Metode statistik yang digunakan uji korelasi Spearman. Hasil: Terdapat korelasi antara kejadian plak, ketebalan tunika intima-media arteri karotis dan total calcium score dengan derajat stenosis arteri koroner, dimana nilai p masing-masing secara berurutan yaitu 0,017 (<0,05), <0,0001, dan <0,0001 dan nilai r masing-masing yaitu 0,418, 0,65, dan 0,882. Simpulan: Skor kalsium total merupakan suatu penanda independen risiko kejadian kardiovaskular, lebih superior dibandingkan evaluasi arteri karotis. Terdapatnya nilai skor kalsium total menunjukkan adanya suatu penyakit arteri koroner namun tidak memprediksi obstruksi luminal. Di samping itu, keadaan dinding arteri karotis juga dapat mencerminkan keadaan dinding arteri koroner sehingga dapat digunakan sebagai penanda terjadinya aterosklerosis pada pembuluh darah jantung pada daerah yang belum memiliki fasilitas skor kalsium total.
Pendahuluan: Penelitian ini bertujuan untuk menilai gambaran ultrasonografi kelainan endometrium pada penderita kanker payudara yang mendapat terapi hormonal di Rumah Sakit Wahidin Sudirohusodo. Metode: Penelitian ini dilaksanakan di Rumah Sakit Umum Pemerintah Wahidin Sudirohusodo Makassar mulai bulan Januari sampai bulan Mei 2020. Sampel sebanyak 66 pasien yang telah mendapat terapi hormonal minimal 6 bulan berturut-turut dan dilakukan pemeriksaan ultrasonografi transvaginal. Metode analisis yang dilakukan adalah Uji Chi Square/Uji Fisher dan Uji T Independen. Hasil: Pada penelitian ini, rentang usia terbanyak pasien kanker payudara adalah antara 41 – 50 tahun. Dari 66 pasien yang diteliti, terdapat 34 pasien yang premenopause dan 32 pasien yang menopause. Terdapat 46 pasien yang mendapat terapi Tamoxifen, 20 pasien yang mendapat terapi Aromatase inhibitor. Kesimpulan: Hasil penelitian menunjukkan tidak terdapat hubungan yang bermakna antara penebalan endometrium pada pemeriksaan ultrasonografi transvaginal dengan pemberian terapi hormonal pada penderita kanker payudara dengan nilai p=0,232. Terdapat hubungan bermakna antara status menstruasi dengan penebalan endometrium pada penderita kanker payudara yang mendapat terapi hormonal dengan nilai p=0,002. Terdapat hubungan bermakna antara Indeks Massa Tubuh (IMT) dengan penebalan endometrium pada penderita kanker payudara yang mendapat terapi hormonal dengan nilai p=0,037. Tidak terdapat hubungan bermakna antara penggunaan kontrasepsi hormonal terhadap penebalan endometrium dengan nilai p=0,946. Tidak terdapat hubungan yang bermakna antara nullipara dengan kejadian penebalan endometrium dengan nilai p=0,256
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