The purpose of this study was to evaluate the clinical and functional outcome of Uni-condylar Locking Compression Plating for Extra-articular Distal Humeral Shaft Fractures in adults and comparison with other techniques for management of extra-articular distal humerus fractures. Methods: This Prospective Study was carried out in the

Background: Urinary tract infections (UTIs) attributed to the use of an indwelling catheter is one of the most common infections acquired by patients in health care facilities. This infection is associated with varied microbiological etiology. Catheter-associated urinary tract infection (CAUTI) is an important cause of morbidity and mortality in India. The objective of this study was to find the prevalence of CAUTI infection and to determine their antibiotic profile. Aims and Objectives: The aim of the study was to provide a baseline information in the context of culture positivity rate of urinary isolates and prevalence of catheter associated urinary tract infections (CAUTI), to identify the associated microbial, and to determine their susceptibility pattern to commonly used antimicrobial agents for prophylactic and empiric therapy. Materials and Methods: This prospective study was done on nonrepetitive urine samples from all age group patients of both inpatient and outpatient department. Semi quantitative bacterial culture was performed, and isolates were identified and antimicrobial sensitivity tests were carried out by Vitek-2 compact automated method. Results: Significant bacteriuria was observed among 257/1543 (16.65%) urine samples. Among bacterial isolates, Gram negative bacilli predominate. Escherichia coli 7/17 (44%) being the most common isolate followed by Klebsiella (35%). The incidence of CAUTI/1000 catheter days observed in our study was 2.77. Total 3 CAUTI were identified from July 2021 to June 2022, out of which 2 were Klebsiella pneumoniae and 1 isolate was Enterococcus faecium. Conclusions: Uropathogens from CAUTI patients exhibit significantly higher resistance to most antibiotics than non- CAUTI isolates. This is an important factor to take into consideration when choosing correct treatment options for patients with urinary tract infection. Klebsiella pneumoniae is one of the important notable pathogens causing nosocomial infections.............

<p class="abstract"><strong>Background:</strong> Total knee replacement (TKR) is associated with substantial blood loss and thus the need for blood transfusions. Risks and costs of allogenic blood transfusions requires strategies to reduce blood loss in surgery. The objective of this study was to assess the efficacy of tranexamic acid treatment in reducing blood loss and blood transfusion requirements during TKR.</p><p class="abstract"><strong>Methods:</strong> A randomized controlled trial was conducted on 60 patients who were operated for unilateral TKR from January 2016 to January 2019 in Shadan Institute of Medical Sciences. 30 patients were in each control and study groups. In study group 12 mg/kg bolus of tranexamic acid was given as a slow IV dose, 40 minutes before deflation of tourniquet followed by 1.2 mg/kg/hr infusion for 12 hours with standard treatment of hospital and compared to the control group. Later blood loss was compared both intra and post operatively. Fall in haemoglobin after surgery was also compared.<strong></strong></p><p class="abstract"><strong>Results:</strong> Total blood loss in tranexamic acid group was 543.3±184.85<strong> </strong>ml (control group 685.83±176.74 ml) which is statistically significant (p&lt;0.05). Blood loss was markedly decreased in tranexamic acid group (379.16±174 ml in tranexamic acid vs. 513.33±143.89 ml in control group) statistically significant (p&lt;0.05).</p><p class="abstract"><strong>Conclusions:</strong> Tranexamic acid is an effective strategy to reduce blood loss in patients undergoing total knee replacement and thus minimizing the need for blood transfusions.</p>

Background: Arthroscopic anterior cruciate ligament reconstruction is commonly performed with intent to return earlier to normal activities, so graft selection becomes more important. The use of hamstring tendon autograft is supposed to have less postoperative morbidities. In this prospective study we assess the early post-operative complications. Methods: 25 patients were operated in Shadan by the same surgeon and were assessed preoperatively, and 3 and 6 months after surgery. The hamstring and quadriceps strength were measured with PRIMUS RS machine. The patients were also assessed for their subjective complaints using International Knee Documentation Committee (IKDC) knee scoring system. Results: The peak power of flexion and extension of the knee joint significantly improved following the surgery which is essential for any athletic activities. Quadriceps and hamstring strengths were restored to 90%, which suggests that the grafting has been successful in restoring isometric strength. This is necessary to return to sporting activities. Power of hamstrings and quadriceps significantly improved following surgery. Quadriceps and hamstring endurance recovered and improved at the end of 6 months following surgery. Using IKDC scoring, nearly normal were 14, normal were 10 and abnormal 1. 3 patients (12%) presented with anterior knee pain. Sensory loss was noted in 6 patients (24%) at the end of 6 months following surgery. Swelling was noted in 5 patients (25%). Conclusions: Most morbidities are temporary in nature and do not significantly affect the patient's activities.