Nephrotic Syndrome (NS) is a common childhood illness characterized by massive proteinuria, hyperlipidemia, hypoalbuminemia & edema. NS is a disease of relapse and it is a major problem to manage the cases with frequent relapse. So it is very important to find out such children who are prone to develop frequent relapse. This retrospective study was conducted in the paediatric department of Dhaka Medical College Hospital (DMCH) from January to December 2005.Total 100 children with relapsed NS of them 50 had Frequent Relapse NS (FRNS) and 50 had Infrequent Relapse NS (IFRNS) were included in the study with a view to find out the risk factors for relapse. Data were collected from previous medical and hospital records. Data were analyzed by using SPSS program. Chi-squared test and Student's t-Test were used as statistical test and p value < 0.05 was taken as significant. NS was more common among 2-6 years of age (67%) with male to female ratio roughly 2:1. Most of patient with frequent relapse had age <5 years, came from rural area and belongs to poor social class compared to that of infrequent relapse. The mean age at first onset was significantly less in frequent relapse group than that of infrequent relapse group. Majority of atopic child belongs to frequent relapse cases. Low serum albumin level, low serum total protein level, culture positive Urinary Tract Infection (UTI) at initial attack were observed to be statistically significant in case of frequent relapse group.DOI: http://dx.doi.org/10.3329/fmcj.v7i1.10292Faridpur Med. Coll. J. 2012;7(1): 18-22
Context: Hepatitis C virus is one of the leading causes of liver disease and represents a major public health problem. It is a common cause of cirrhosis and hepatocellular carcinoma (HCC) as well as the most common reason for liver transplantation. Methods: A cross sectional study was carried out during the period of April 2007 to April 2008 among health care workers including phlebotomists, dialysis staffs and laboratory personnel handling blood and blood products. Total 200 health care workers from phlebotomists working at one stop collection centre of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka Medical College Hospital (DMCH), Dialysis staff working at haemodialysis units of BSMMU, Bangladesh Institute of Rehabilitation for Diabetes, Endocrine & Metabolic Diseases (BIRDEM), DMCH, National Institute of Kidney Diseases & Urology (NIKDU) had at least more than one year working exposure was enrolled in this study. After taking informed written consent detailed history was taken, clinical examination was done. 0.3 ml of venous blood was collected from each patient and tested for anti HCV by commercial kit, confirmed by ELISA method. Result: Among 200 patients majority (55.5%) of patients were below 30 years of age and there was equal prevalence among male and female. Out of 200 health care workers 1% was found to be anti HCV positive. All positive patient had duration of exposure of >5 years and had history of needle stick injury. Key words: Hepatitis C virus; seroprevalence; health care workers. DOI: 10.3329/jdmc.v18i1.6310 J Dhaka Med Coll. 2009; 18(1) : 70-74
Hepatitis C virus is one of the leading causes of liver disease and represents a major public health problem. It is a common cause of cirrhosis and hepatocellular carcinoma (HCC) as well as the most common reason for liver transplantation. This cross sectional study was carried out during the period of April 2007 to April 2008 among thalassemic patients with history of multiple blood transfusion (>20 units). Total 200 thalassemic patients from Thalassemia Samity Hospital, Green Road, Bangladesh Thalassemia Foundation, Dhanmondi, and from Department of Transfusion Medicine, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka were included in the study.After taking detailed history and clinical examination , 0.3 ml of venous blood was collected from each patient and tested for anti HCV by commercial kit. Positive cases were confirmed by ELISA method. Among 200 patients majority (68.5%) were below age of 20 years with a male to female ratio of 1.7:1,16.5% were found to have anti HCV positive. Anti HCV positivity increased with duration of exposure and number of blood transfusion., 22.9% of patients who had duration of exposure for more than 10 years and 36.4% having blood transfusion more than 40 units were positive for anti HCV. Key words: Seroprevalence; hepatitis C virus; thalassemia. DOI: 10.3329/jdmc.v18i2.6269 J Dhaka Med Coll. 2009; 18(2) : 115- 119
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