Oil and Gas Industry (OGI) faces a number of evolving and various types of risks and hazards that give rise to serious incidents. To conduct this study 801 incidents reports have been numerically analyzed, evaluated and interpreted. These incidents reports covered various severity levels, which have been occurred in 6 regions across the world, from 2014 to 2016. The analysis focused on global oil and gas industry. The study has shown that Occupational Work-related Incidents (OWRIs) occur mostly in October and especially in spring time. In addition, it has pointed out that the region of North America is the most affected area; almost one-third of OWRIs occurs in turbine hall area. Surprisingly, the study also revealed that three-quarters of the OWRIs did not occur in High-Risk Activity (HRA) and half of the incidents took place with no tooling involved. Noticeably, the main recurrent and frequent event was struck against or by (SAoB) that resulted dominantly in slight injuries that required only first aid care, and the most affected body part is the finger by “Cut (Laceration)/ Pinch”. The study has confirmed that the hazardous working environment in OGI was the direct cause for half of the OWRIs. However, based on the revealed results, it will be the assumptions that human factors have a crucial impact on the workplace safety and a contributing factor in the incidents. Some control measures were suggested accordingly.