Background:The exposure of free radicals can induce oxidative stress. In the liver, this process will cause impaired liver function. Oxidative stress can be inhibited by antioxidants. Arrowroot tubers (Maranta arundinacea) contains phenolic, flavonoid, alkaloids and saponin compound that are potential as antioxidants. Objective: Determine the effect of ethanolic extract of arrowroot tubers (Maranta arundinacea) against oxidative stress using the parameter of MDA, SGPT and SGOT level in ethanol-induced rats. Methods: Animal models were divided into 5 groups, in which each group contained 6 rats. Group I (normal) and group II (control) was induced with CMC Na 0,5%. Group III, IV and V were given ethanolic extract of arrowroot tubers in the dosage of 125, 250 and 500 mg/Kg/day respectively. The extract was administered orally for 14 days. Induction of ethanol 5 gram/ KgBW was administered orally 1 hour after the last administration on day 14th except for group I. On day 15th, the animal blood was drawn to measure the levels of SGPT and SGOT, then the animals were sacrificed and their organs were analyzed to measure the levels of MDA in the liver. Data obtained in the form of MDA, SGPT and SGOT levels were statistically analyzed using ANOVA. Results: There is statistically significant difference between the utilization of ethanolic extract of arrowroot tubers (Maranta arundinacea) group with the control group in reducing the concentration of MDA (p<0,05), SGPT, and SGOT (p<0,05). Conclusions:The ethanolic extract of arrowroot tubers (Maranta arundinacea) is able to reduce the concentration of MDA, SGPT and SGOT in ethanol-induced rats.

The use of Moringa leaves is increasing because it contains β carotene, phenolic compounds and flavonoids which are efficacious as antioxidants. The solvent concentration is a factor that affects the active content in the extract. This study aims to determine the effect of ethanol concentration on β carotene levels, total phenolic and total flavonoids in ethanol extract of Moringa leaves. In this study the variation of ethanol solvent concentration was 50%, 70% and 96% for extracting Moringa leaves by maceration method at a ratio of 1:40. The extract obtained was determined as β carotene levels by using HPLC, total phenolic content and total flavonoids contend by spectrophotometer. The results of each test were analyzed by using one-way ANOVA to see a significant difference between solvent concentrations for each test parameter. The test results showed that in each ethanol extract 50%, 70%, 96% had β carotene levels of 0.24 ± 0.01; 0.40 ± 0.00; 5.33 ± 0.15; total phenolic 122.26 ± 1.49; 132.54 ± 2.56; 84.62 ± 2.44; total flavonoids 2.51 ± 0.06; 5.03 ± 0.08; 13.15 ± 0.47, respectively. The highest solvent containing active ingredients is 96% ethanol.