Amyloidosis refers to a group of protein misfolding diseases characterized by deposition of a particular amyloid protein in various organs and tissues of animals and humans. Various types and clinical forms of amyloidosis, in which the pathology and pathogenesis is diverse depending upon the underlying causes and species affected, are reported in domestic and wild animals. The clinical findings are also quite variable consequent to the variation of the tissues and organs involved and the extent of functional disruption of the affected organs in various animal species. The affected organs may be enlarged and exhibit variable pallor grossly, or the amyloid deposit may be discernible only after microscopic examination of the affected tissues. Amyloid appears as a pale eosinophilic homogenous extracellular deposit in tissues. However, microscopic examination and Congo red staining with green birefringence under polarized light are needed to confirm amyloid and differentiate it from other apparently similar extracellular deposits such as collagen and fibrin. Identifying the type of amyloid deposit needs immunohistochemical staining, ultrastructural characterization of the amyloid fibril, and if feasible also genetic studies of the involved species for clinical and prognostic purposes. This paper provides a concise review of the occurrence of amyloidosis in domestic and wild animals.

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A survey of sarcocystis was made in camels from southern Ethiopia during a part of 1998-99. A total of 605 haematoxylin and eosin-stained tissue samples from cardiac, diaphragm, shoulder, masseter and oesophagus muscles of 121 adult camels and 20 tissue samples from four foetuses were examined for sarcocysts. Sarcocysts were detected in 55 of 121 (45.45%) camels examined. The infestation rate of oesophagus, diaphragm, shoulder, masseter and cardiac musculatures were 19.83, 11.57, 12.4, 8.26 and 9.17%, respectively. There was no significant (P > 0.05) variation between males (48.6%) and females (40.82%), nor between the two sites studied (Dollo Addo, 40.00% versus Neghelle Borana 47.25%). None of the 20 tissue samples from the four foetuses examined harboured sarcocysts. The possible impact of sarcocysts on camel production is indicated. This is the first report of the presence of sarcocysts in camels from Ethiopia.