Dans le but de connaître les plantes médicinales utilisées traditionnellement par la population de la ville de Kénitra (Nord ouest du Maroc), une étude floristique et ethnobotanique a été réalisée dans cette région. L'étude de la flore médicinale a permis d'inventorier 62 espèces appartenant à 34 familles et 58 genres. De même, une série d'enquêtes ethnobotaniques réalisées à l'aide d'un questionnaire, a permis de collecter un certains nombres d'informations. Les résultats de cette étude ont montré que le feuillage constitue la partie la plus utilisée. La majorité des remèdes est préparée sous forme de décoction. Sur l'ensemble des maladies traitées, les affections digestives représentent les maladies les plus citées.

Background: The aim of these studies was to assess the potential of the Rif (northern Morocco) with regard to medicinal and aromatic plants used in the treatment of respiratory system diseases. Methods:The ethnobotanical and ethnopharmacological studies were conducted in the Rif region for two campaigns (June 30th, 2016 to June 1st, 2018). In total, 674 local traditional healers were interviewed. Information was collected using open-ended and semi-structured interviews, analyzed and compared by quantitative ethnobotanical indices such as family importance value (FIV), relative frequency of citation (RFC), plant part value (PPV), fidelity level (FL) and informant consensus factor (ICF) were used to analyze the obtained data. Results:The study identified a total of 41 medicinal plant species belonging to 22 botanical families. The most important family is that of the Lamiaceae represented by 8 species. Concerning the diseases treated, Asthma have the highest ICF (0.97), the leaf was considered the most used part of the plant (PPV=0.482) and the majority of the remedies were prepared in the form of decoction. Conclusions:The results of these present studies showed the existence of indigenous ethnomedicinal knowledge of medicinal and aromatic plants in the Rif to treat respiratory system diseases. Further research on phytochemical and pharmacological should be considered to discover new drugs from these documented plants.

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Using a slight modification of the crown-gall potato disc bioassay, we were able to apply this test for two previously described antineoplastic lipophilic metabolites, didemnin B and mediterraneol A [1], and to use it as a guide for chromatographic separations of meroterpenoids from Cystoseira mediterranea. An active compound, mediterraneone [3], was isolated, and its structure was found to be a novel norsesquiterpenoid by chemical and spectral methods.