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We are trying to illustrate operative, short-term, and pathological outcomes of transanal total mesorectal excision (TaTME) as a surgical procedure for patients who are suffering cancer in the lower or middle rectum. This study included 25 consecutive patients who underwent TaTME for the mid and low cancer rectum. The primary outcome measures included frequency of postoperative (PO) bleeding, leakage, ileus, days to regain bowel function, days for Foley's removal, and erectile function. The secondary outcome measures included operation time, status of resection margins, number, the quality of TME, and duration PO hospital stay. No recorded intraoperative complications. The mean hospital stay was 6.9 ± 2.6 days. The mean duration need for urinary catheter removal and flatus passage were 2.4 ± 2.1 and 1.5 + 0.9 days, respectively. The mean IPSS was returned to normal 12 months after surgery. The mean distal margin distance was 1.9 ± 1.1. Circumferential margin distance was > 1 mm in 23 (92%) patients. The mesorectum was complete in 22 (88%) patients. The survival rate was 88% over 3 years. TaTME could be considered as a safe, feasible, and effective surgical modality for patients who had mid and lower rectal tumors with an excellent pathological outcome.

Trichinellosis is a zoonotic disease of public health concern since it caused human outbreaks in many countries. Traditional therapy has many adverse effects in addition to the developing resistance. So, this necessitates finding effective natural alternatives. The study assessed the effect of Thyme extract (active constituent of thyme) on Trichinella spiralis in experimentally infected mice compared with Albendazole ® .One hundred and twenty Albino mice were classified into four groups of 30 mice each. G1: non-infected control, G2: infected untreated control, G3: albendazole treated, and G4: thyme extract treated. Mice were sacrificed on the 7 th day post infection for intestinal phase and on the 49 th & 60 th days post infection for muscular phase. Efficiency of treatment was assessed by parasitological and histopathological examinations.The results showed significant decrease in intestinal worms in all treated mice relative to untreated control group. Reduction rates regarding the intestinal phase was 96.7% in albendazole treated mice, followed by 33.4% in Thyme extract treated ones. Histological showed a significant decrease in muscle larvae relative to positive control mice showed by reduction rates of 86%, & 45.1% for albendazole and thyme respectively on 49 th dpi, and 99.9 %, & 68.6% respectively on 60 th dpi. There was improvement in intestinal and muscular architecture in all treated mice compared to positive control one, which was markedly best in albendazole treated ones.

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