Background:Wart is a common transferable skin disease that is caused by human papilloma virus. Choosing the best treatment method can vary based on age, therapeutic goal, complications, and wart place. Due to antibacterial effect of shallomin (hirtifolium Boiss extract) and since its effect has not been studied yet, it was compared to cryotherapy therapeutic methods for treating patients with plane warts.Methods:The present study was a randomized clinical trial that was carried out on 40 patients. Sampling was conducted simply by 4 block randomization method. The selected patients were assigned into two Groups of A and B. Data analysis was conducted by descriptive methods, and then, statistical tests including Chi-square, Fisher's exact test, and t-test were run to determine the relationship between qualitative and quantitative variables. In so doing, SPSS software version 16.0 was utilized.Results:Comparing the means showed that as opposed to cryotherapy, shallomin could not lead to a significant decrease in the size and number of warts.Conclusion:According to the results of this study, which is the first and the only investigation into the effects of shallomin on treating plane warts, it can be stated that despite of its antibacterial, antifungal, and anti-herpetic properties, shallamin cannot be a clinically effective option for treating plane warts.

Atrophy and wrinkling of the skin, elevation of bones, and bulging of the veins and tendons are among outstanding characteristics of hand aging. In recent years, there has been an increase in demand for apparent rejuvenation of the hand. A review of the research literature shows that there are many options for rejuvenation of the hand including peeling agents, removal of dead micro-dermal layers, and dermal fillers. The present study was an attempt to consider and describe autologous fat transfer to the hands. In so doing, the databases of PubMed, Google Scholar, and Science Direct were searched, and out of the retrieved 1988 articles, 30 were used in the present review. The analysis carried out by the researchers showed that autologous fat transfer is the most promising method that has recently drawn lots of attention.

Identifying the cutaneous symptom associated with HIV positive disease and investigating the kind of rashes can be helpful in early diagnosis of the disease. The extensity of skin disorders in HIV infection is widespread. Examination of the skin of these patients can be a good indicator of the status of the immune system as well as the patient's psychological status and also in early diagnosis can make a worthy help. We carried out a literature search (From 1990(From to 2016 related to this issue through Google Scholar, Pub-MED, Scopus, Science Direct, and Iran DOC, by using keywords cutaneous symptoms, HIVpositive, skin infection, warts, early diagnosis. Among 124 articles only 51 papers were related to skin infections. Review of the associated research, investigation the skin infections in HIV patients and early diagnosis made a great help in the treatment process, particularly in people with high-risk behaviors which leads to diagnosis the HIV in the early stages. The results of this study suggest the importance of cutaneous symptom in patients with HIV infection and early diagnosis to start the medical procedures.