There was no significant effect of crocin on serum anti-Hsp27 titers in subjects with MetS, but this needs further confirmation in larger-scale trials.
form may, in the long run, develop isolation resulting in avoidance of social relationships in individuals and in more severe cases depression and mood disorders. 2,3 Essentially, the reason people go to dermatologists is to improve the beauty and appearance of their face and to achieve a more attractive look with the aim of maintaining and strengthening their position in the family and among their friends as well as in the community. 4 Therefore, the causal relationship between beauty preservation in the face and appearance and reduced risk of future mood disorders is to be expected. Even more recently, beauty preservation procedures have been used as alternative therapies in patients with depression leading to favorable outcomes. 5,6 Botulinum toxin type A is now globally used for beautifying facial components by temporarily paralyzing the facial muscles. The
This study demonstrates that at a dose of 30 mg per day for 8 weeks, crocin reduced the symptoms of depression in subjects with MetS compared to the control group, and this effect was independent of its effect on the serum PAB.
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