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Cancer is the leading cause of mortality in the world. The major therapies for cancer treatment are chemotherapy, surgery, and radiation therapy. All these therapies expensive, toxic and show resistance. The plant-derived compounds are considered safe, cost-effective and target cancer through different pathways. In these pathways include oxidative stress, mitochondrial dependent and independent, STAT3, NF-kB, MAPKs, cell cycle, and autophagy pathways. One of the new plants derived compounds is Polyphyllin VII (PPVII), which target cancer through different molecular mechanisms. In literature, there is a review gap of studies on PPVII; therefore in the current review, we summarized the available studies on PPVII to provide a base for future research.

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One of the major divisions in analysis and design of tall buildings is to account for forces induced by flying‐object impact and the subsequent progressive collapse. During the past three decades, problems of contact mechanics have been considered by some authors, and special attention has been devoted to high‐speed impact. Impact wave propagation in tall buildings may be analysed using the conventional finite element method. However, in order to guarantee stability and accuracy of the solution, the number of elements used to model the structure may be very large indeed; more precisely, accurate results can be obtained after a substantial computational effort. In this respect, an improved complex spectral element method is developed for analysing the wave propagation problems in large structures. The purpose of this paper is to obtain the resulting dynamic responses of a tall building induced by a high‐speed impact of a flying object. Copyright © 2003 John Wiley & Sons, Ltd.

One of the major divisions in the mathematical modeling of a tubular structure is to include the effect of the transverse shear stress and rotary inertia in vibration of members. During the past three decades, problems of vibration of tubular structures have been considered by some authors, and special attention has been devoted to the Timoshenko theory. There have been considerable efforts, also, to apply the method of spectral analysis to vibration of a structure with tubular section beams. The purpose of this paper is to compare the results of the improved complex spectral element method for the Timoshenko theory with those derived from the conventional finite element method for an offshore structure. Using a computer program, the proposed formulation has been extended to derive the dynamic response of an offshore platform structure under dynamic loads.