Diabetes is characterized by chronic hyperglycemia and disturbances of carbohydrate, lipid and protein metabolism. We aimed to estimate the cardiovascular risk factors and their correlation with type 2 diabetes mellitus (T2DM) in Zanzibar (Mnazi MMoja Hospital) hypothesizing that early detection and treatment of lipid abnormalities can minimize the risk for atherogenic cardiovascular disorders and cerebrovascular accident in patients with T2DM. Methods: The study populations were those patients who presented themselves at Mnazi Mmoja hospital with T2DM, and who are within the age bracket of 18 to 45 years. Fasting blood glucose (FBG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), and triglyceride (TG) levels were evaluated. Pearson’s correlation studies were performed between the variables of blood glucose and serum lipid profiles and also within the lipid profile parameters. Results: TC, TG, LDL-C mean levels were significantly higher in diabetics compared with the control subjects p< 0.05. The HDL-C was however lower in diabetics compared with the controls. Also, the mean FBG, TC, TG, and LDL-C were significantly higher in female diabetic subjects compared to the male counterparts p< 0.05. A positive correlation was observed between FBG and TC, TG and LDL-C (r=0.643 p=0.0021; r=0.679, p=0.0001; r=0.534, p=0.0091 respectively) while HDL-C showed a negative correlation (r= -0.799, p= 0.0021). TC also showed a positive correlation with TG and LDL-C (r=0.590, p=0.0021; r= 0.628, p=0.0001) and negative correlation with HDL-C ( r=-0.670, p=0.0041). Conclusion: There is an influence of gender on cardiovascular disease risk factors with more of the females seriously at risk. Measurement of serum lipid profile should be introduced to the management plan of diabetes mellitus. There is an urgent need for the establishment of regional and national training courses for diabetic educators and also the creation of new evidence-based management plan for diabetics in Zanzibar for a better healthcare.
Introduction: Worldwide, traumatic head injuries account for a high degree of morbidity and mortality. Road accidents appear to be the commonest cause of these injuries. This study is aimed at assessing the prevalence and predictive factors of Traumatic head injury at a tertiary institution health facility in Zanzibar. Method: A retrospective observational study of head injury patients that are attended at Mnazi Mmoja Hospital, Zanzibar from May 2019 to May 2020 Results: A total number of 81 patients were included in the study and distributed as follows; 63 males (77.8%) and 18 females (22.2%) participants. The majority of patients were between the age group of 16-30 years and 40 (49.4%) in total. Road Traffic Accident was the leading cause of injuries (67.9%). Others include assault (13.6%), falling (13.6%), and being struck by an object (4.9%). The study also recorded a higher prevalence of traumatic brain injury TBI (57.9%), including, concussion (9.8%), contusion (18.5%), epidural hematoma (8.6%), skull fracture (14.8%), and subarachnoid hemorrhage (6.2%). This was compared with other causes of head injuries (42.1%) such as cut wounds (9.8%) and soft tissue injuries (32.1%). 64.2% of the patients were treated as outpatients, with 33.3% as inpatients. About 2.5% of the patients died. The west district recorded the highest prevalence of patients with injury rates compared to other districts. Conclusion: Public awareness campaigns and health promotions concerning road safety rules are needed to help reduce the high burden of road traffic accidents. Government should also pay attention to the improvement of roads as a way to curb this menace.
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