This  study   aimed  to  identify  of  maqasid  syariah  and   its  importance  in  the  interpretation  of  laws  in  the  Quranic  verses.   This  study  also  aimed  to  analyze  maqasid  syariah  in  the  interpretation of  alcohol laws in the Quran  verses which were applied by Hamka  in Tafsir  al-Azhar.  This study used texts and contents analyses. Inductive, deductive and comparative methods were also used to analyze the data. The  main result  of  this  study showed  that  the maqasid  syariah  was  applied  by  mufassir  in  interpretation  of the  laws  in  the  Quran  verses.  The  study found  that  Hamka  has  applied  the  maqasid  syariah  in  the interpretation  of  alcohol  laws in  the  Quran  verses  in  Tafsir  al-Azhar.  This  study concludes  that the application  of  maqasid  syariah  in  the  interpretation  of  law verses in  the  Quran should be emphasized  by mufassir.  The collection of law verses is important to facilitate Muslims to refer and practice them. The implication  is that the study has  created  a  maqasidi  thematic  interpretation  methodology  and  it  can  be  used  as  a  method  to interpret law verses in the Quran.