Fungi have emerged as an important cause of health-care associated infections (HCAI) in last few decades. spp. is the most common cause of invasive fungal infections (IFI) in hospitalized individuals. The present study was conducted in a tertiary care teaching hospital with an aim to study species distribution and antifungal susceptibility pattern of isolates from cases of HCAI. isolates from cases of HCAI from medical intensive care unit were identified up to species level. Antifungal susceptibility testing of isolate was done by Clinical and Laboratory Standard Institute (CLSI) broth microdilution (BMD) method. The rate of CA-UTI due spp. was 0.3 per 1000 catheter associated days. The rate of catheter related BSI was 0.9 per 1000 catheter associated days. Predominance of non spp. over was noted. Fluconazole resistance was significantly high in NAC spp. compared to .

Although, bacteria have been considered as most common cause of healthcare associated infections (HCAI), however recent years have witnessed increased isolation of fungal pathogens. species, Mucorales, spp., spp. and spp. are predominant fungal pathogens isolated from cases of HCAI. As compared to bacterial nosocomial infections, fungal infections are generally difficult to diagnose and treat. Nosocomial mycoses are associated with high mortality and morbidity. The present study was conducted in the tertiary care academic hospital with an aim to identify filamentous fungal pathogen isolated from HCAI and study its antifungal susceptibility profile. Filamentous fungi isolated from cases of HCAI from intensive care unit (MICU) were included. They were identified by standard mycological techniques and antifungal susceptibility profile was studied. Out of 50 fungal pathogens, spp. were isolated from 21 (42%) cases, whereas 29 (58%) isolates were filamentous fungi. spp. (51.7%) were predominant among filamentous fungal pathogen. (27.6%) was the predominant isolate. Use of broad-spectrum antibiotics followed by neutropenia and presence of indwelling medical devices were common risk factors associated with HCAI due to filamentous fungi. Amphotericin B resistance was observed in 6.9% of isolates whereas 33.3% were resistant to fluconazole. Invasive fungal infection (IFI) though less common is associated with increased morbidity and mortality in patients admitted to ICU. Neutropenia and use of broad spectrum antibiotics are important risk factors for IFI. is the most common filamentous fungus cause of IFI. More emphasis should be given on rapid diagnosis, prompt treatment and strict compliance with infection prevention and control practices.