PNI and CONUT are potential tools for nutritional assessment in patients with chronic liver disease, especially for ordinary medical care, because of their simplicity.
Abstract. Body cell mass (BCM) is a nutritional parameter, however, changes in BCM in patients with non-ascitic liver cirrhosis (LC) in comparison to patients with other malnutritional diseases remains unclear. We investigated the difference in BCM between patients with LC and malnourished gastrointestinal disease controls (M.CON), and examined the relationship between BCM and the severity of LC. Results demonstrated that serum nutritional parameters were not significantly different between the LC (n=56) and M.CON groups (n=25), whereas BCM%BW was significantly lower in the LC group than in the M.CON group (50.9±4.6 vs. 54.4±7.1%, P=0.018). Furthermore, BCM%BW negatively correlated with the model for end-stage liver disease (MELD) score (P=0.04). In concluson, BCM showed a significant decrease and a negative correlation with the MELD score in the LC group. BCM may be a useful parameter for assessing malnutrition and severity of
Introduction ‐ Acetylcholine (ACh) is a well known neurotransmitter in the central nervous system, but determining its level in cerebrospinal fluid (CSF) is very difficult and the origin of CSF ACh is still unknown. In this study, we attempted to measure CSF ACh by a specific and sensitive radioimmunoassay (RIA) from patients with neurologic diseases. Material and methods ‐ Patients with cerebral infarction (n= 7), Parkinson's disease (n= 6), spinocerebellar degeneration (n= 6), Alzheimer's disease (n= 3), amyotrophic lateral sclerosis (n= 3) and disc herniation with no central nervous involvement (n= 8) participated to determine the CSF ACh levels. Results ‐ Of these 33 patients, the mean ACh level in CSF was 282.2 ± 61.7 fmol/ml (mean ± SE, range 20–1505.8 fmol/ml). The mean ACh level of spinocerebellar degeneration group was lower than others, but not statistically significant. Conclusion ‐ We conclude that an amount of ACh detectable by RIA is certainly present in CSF
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