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Introduction: Duchene Muscular Dystrophy (DMD) is

Sambalpur is considered as the rice bowl of Odisha for its cultivation activities due to the presence of hydroelectric power house Hirakud Dam, with total capacity of  5,896,000,000 m3, 55 km long and is one of the first major multipurpose river valley projects started after India's independence. It irrigates about 75,000 km2 (19×106 acres) of land and therefore, is considered as a blessing to the farmer families. As because of cultivation and allied activities, Agricultural Laborers (ALs) constitute a large portion of the active work force. Study on the nutritional intake in this important fraction of population is lacking. Present study was an attempt to know the food consumption pattern and nutritional intakes of ALs in Hirakud command area of Sambalpur district, India. Data were collected from 300 ALs, consisting of 150 from each gender. Daily dietary pattern and nutritional intake of respondent were calculated through 24 hours dietary recall method. It was observed that ALs consume all most all the food varieties available in Odisha. Cereal consumption was 6.80 and 1.77 % excess than the recommend value dietary allowance (RDA) by Indian Council for Medical Research (ICMR, in 1990). Except cereals, all other food consumption was below the RDA value in ALs. The intake of other food varieties in ALs was > 60% deficit from the RDA values. Consumption of milk was 97% less in case of male ALs and 98 % less in case of female ALs in comparison to the values suggested in RDA. Similarly, consumption of all nutrients was less than RDA norms except Vitamin -C in case of male ALs. The consumption of Niacin and Vitamin -C was excess in case of female ALs. Alternate low cost food supply is suggested to compensate such insufficient nutritional uptake by ALs in the study area. Keywords: Food, nutrient intake, nutraceuticals, nutritional status, 24 hours recall method

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Background: Non-Rhesus D antigen non-ABO, minor blood group alloimmunization in pregnant women is being increasingly recognized as a significant contributor to the development of the hemolytic disease of the fetus and newborn (HDFN). We report severe HDFN in a neonate born to an Rh-positive mother with sickle cell disease, following anti-C and anti-S alloimmunization. Clinical Description: A male baby born to a repeatedly transfused mother with sickle cell disease developed severe jaundice at 22 h of life. The baby was found to have severe anemia and indirect hyperbilirubinemia, but no encephalopathy, hepatosplenomegaly, or features of sepsis. Management and Outcome: His blood group was O positive and the direct Coombs test was 4+. Minor blood group typing showed the presence of anti-C and anti-S antibodies. The baby improved after receiving a double-volume exchange transfusion with matched blood and phototherapy. Conclusion: Severe hemolytic disease of the newborn (HDN) may be caused by minor blood group alloimmunization, especially seen in mothers with a history of multiple transfusions. Antenatal screening for alloimmunization in high-risk mothers can ensure timely diagnosis and treatment of HDN and prevent the harmful effects of neonatal hyperbilirubinemia.