BACKGROUND: COVID-19 virus continues to be an international concern, challenging psychological resilience in all areas, especially virtual education, making the psychopathology and problems more evident. MATERIALS AND METHODS: The present study is a qualitative study of conventional content analysis, in which 24 participants (14 parents, 5 teachers, and 5 principals) were selected by purposive sampling from primary schools in Zahedan. Data collection tools included semi-structured interviews with open-ended questions. Interviews continued until reaching data saturation. The transcripts of the interviews were coded according to Graneheim and Lundman's 5-step approach, and then, the codes were classified according to the specified axes. For accuracy and exactness of information, the researchers used the criteria of validity, verifiability, reliability, and transferability. RESULTS: The results of this study include two categories, “e-learning infrastructure” and “psychopathology,” indicating the importance of creating, using, and strengthening cyberspace infrastructure for the use of education in primary schools during COVID-19 pandemic. CONCLUSION: The results indicated that identifying these cases and attempting to eliminate them can reduce psychopathology and improve the quality of virtual education for students. Moreover, this can help principals and educational planners have new insights so that they can focus on solving psychological problems in e-learning and provide their supportive planning.