Surgical removal is the treatment of choice for subcutaneous (SC), intermuscular (InterM), and intramuscular (IntraM) mast cell tumors (MCTs). Advanced imaging (CT or MRI) is frequently used for presurgical planning, but InterM and IntraM MCTs can be difficult to identify and delineate on CT. Aims of the current retrospective, diagnostic accuracy, observer agreement study were to describe the imaging features of SC, InterM, and IntraM MCTs on CT and to assess the limitation of CT to identify the full local extent of the MCT. Inclusion criteria for the study were dogs with a cytologically or histologically diagnosed MCTs determined to be SC, InterM, or IntraM MCT based on histology and/or a CT scan performed in the gross disease setting.Two board-certified veterinary radiologists reviewed the CT images and recorded location, contrast enhancement pattern, and delineation between the normal and abnormal tissue. Sensitivity and specificity of CT for determining location (SC/InterM versus IntraM) was 85.71% and 55.56%, respectively, when compared to consensus location based on surgical pathology report/CT/MRI review. There was a low interrater agreement for delineation (kappa: 0.150 (−0.070 to 0.370) and measurement had a low/moderate correlation (rho: 0.4667 to 0.5792). Upon review by a surgical oncologist, CT findings were deemed insufficient for curative surgical planning in 13 of 16 due to inadequate definition of tumor depth, compartment boundary (fascial plane) or MCT margins. The use of CT for presurgical planning of SC/InterM/IntraM MCT dogs has limitations, especially when differentiating MCT from the adjacent muscle.
The adsorption isotherms for methanol on hydrophilic and hydrophobic Aerosil, and on a solid mixture of both, are used to show that the effect of the hydrophobicity on the well known interaction between alcohols and the surface of silica manifests itself not on the energetic, but on the geometric characteristics of adsorption.There have been many publications dealing with the adsorption of alcohols on hydrophilic silicas, particularly using methanol as the ads~rbate,l-~ On the other hand, little has been done on the adsorption on mixed solidse4 This paper deals with a series of experiments on the adsorption of methanol, in an attempt to clarify the effect of mixing silicas having varying degrees of hydrophobicity. This work is related to research on the phenomenon of surface heterogeneity that is being followed in this laboratory. During the last 30 years this phenomenon has been interpreted by a large number of models,5 most of them based on the assumption of patchwise heterogeneity. As far as the authors are aware, however, the a priori construction of such surfaces has not been attempted, even though this would certainly clarify some of the assumptions of these kinds of models.
The use of radiation for the diagnosis of various medical conditions is ubiquitous in veterinary medicine, and manual restraint of a patient during X‐ray exposure has become commonplace. Many prospective veterinary students have been involved with radiographs in general practice prior to veterinary school. Their experiences and level of safety training are largely unknown. This prospective survey study involved two web‐based questionnaires that were used to evaluate the experiences, knowledge, and attitudes toward radiation and how these changed following a radiation safety lecture as part of their first‐year curriculum. The questionnaires were distributed to 122 first‐year veterinary students before and after this lecture. All participating students (100%) had worked in a veterinary hospital prior to admission to veterinary school and 79% were involved in making radiographs; however, only 28% reported receiving radiation safety training. The content of the safety training reported was variable. After the radiation safety lecture, students were more likely to report that the radiation safety training they had received was useful, but fewer students reported feelings of safety when using radiation. Despite most students being involved with radiation in practice, few had received radiation safety training, as hypothesized. Contrary to our second hypothesis, a single lecture did significantly improve knowledge and attitudes in several, but not all, instances. Importantly, once students gained knowledge regarding radiation, they placed more importance on its safe use. These results suggest that in‐clinic training of students in radiation safety is insufficient and that lecture‐based training is useful for certain concepts.
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