No abstract

Chorangiopagus parasiticus twins (CAPP) occur due to asymmetric abnormality of monozygous, twinning. It is the commonest form of asymmetric twinning, occurring in 1% of monozygous twins. The asymmetric twin survives by parasitizing the more normally developed co-twin by connecting with the chorionic circulation, hence, chorangiopagus parasiticus. CAPP twin is a markedly edematous foetus with relatively well-developed legs, incomplete pelvis and lower spine. The body cavity contains some incomplete abdominal viscera but usually no thoracic organs. The upper portion of the twin consists of edematous cystic tissue. This parasitic perfused twin has no placental vascular connection and its cord vessels are conjoint with those of the parasitized pump twin on the surface of the placenta or somewhere along the cord. This malformation can be identified by ultrasound as early as 12 weeks gestation.

In this report, we present the case of a rare tumor in the sphenoclival region and discuss the potential pitfalls in its diagnosis and management. Intraosseous lipoma is a rare benign tumor, mostly accounting for 0.1% of all bone tumors. The disease is usually asymptomatic and mainly involves the hips, vertebrae, ribs, and metaphysis of the long bones. However, the intraosseous lipoma of the skull is less common, especially with few cases having been reported to involve the sphenoid bone in the literature. We present a rare case of sphenoclival intraosseous lipoma in a 28-year-old female who presented with a history of chronic headache. A non-contrast computed tomography (NCCT) was ordered, which revealed a deviated nasal septum with thickening of bilateral ethmoidal sinuses with mastoiditis and a well-defined fat-containing intraosseous lesion in the clivus with a mean HU~ of -32 with few septations within. The risk of malignant transformation in intraosseous lipoma is very low. The differential diagnosis of intraosseous lipoma includes end stage of infection, infarct lesions, intraosseous meningioma, angiolipoma, and myxofibrous tumors.

Antibiotic resistance is a major problem and the greatest challenge to both hospitals and in the community. Initially, antibiotic-resistant strains were found to the hospital environment only, but now they can be present everywhere. It was therefore decided to conduct a short-term study on Andrographis paniculata's ability to inhibit the growth of some of the most resistant bacteria in the Doon Valley. Antimicrobial activity of Andrographis paniculate of leaf and steam extract was performed against different MDR isolates. The VITEK2 COMPACT device with a consistent inoculum was used to identify and evaluate the antimicrobial susceptibility of clinical samples obtained in suspected critical patients at Indresh hospitals in Dehradun District. Clinical and laboratory guidelines were followed during the testing process ( Shri Mahent Indresh Hospital). Steam and leaf extract from A. paniculata leaf was tested for antibacterial activities using the disc diffusion method. The present study showing that the leaf extract and steam extract petroleum ether, acetone and ethyle acetate extract are most active against K. pneumoniae, E. coli, Proteus mirabilis, Pseudomonas aeruginosa, Acetinobacter, Pseudomonas sp. , Enterobacterium (MDR strains) and Candia albugin, Aspergillus niger, Fusarium, penicillium (pathogenic fungus.

Chorangiopagus parasiticus twins (CAPP) occur due to asymmetric abnormality of monozygous, twinning. It is the commonest form of asymmetric twinning, occurring in 1% of monozygous twins. The asymmetric twin survives by parasitizing the more normally developed co-twin by connecting with the chorionic circulation, hence, chorangiopagus parasiticus. CAPP twin is a markedly edematous foetus with relatively well-developed legs, incomplete pelvis and lower spine. The body cavity contains some incomplete abdominal viscera but usually no thoracic organs. The upper portion of the twin consists of edematous cystic tissue. This parasitic perfused twin has no placental vascular connection and its cord vessels are conjoint with those of the parasitized pump twin on the surface of the placenta or somewhere along the cord. This malformation can be identified by ultrasound as early as 12 weeks gestation.