In radiation therapy, accurate radiotherapy treatment plan (RTP) reproduction is necessary to optimize the clinical results. Thus, attempts have recently been made to ensure high RTP reproducibility using image-guide radiation therapy (IGRT) technology. However, the clinical use of digital X-ray equipment requires extended quality assurance (QA) for those devices, since the IGRT device quality determines the precision of intensity-modulated radiation therapy. The study described in this paper was focused on developing a multi-energy PbO dosimeter for IGRT device QA. The Schottky-type polycrystalline PbO dosimeter with a Au/PbO/ITO structure was evaluated by comparing its response coincidence, dose linearity, measurement reproducibility, linear attenuation coefficient, and percent depth dose with those of Si diode and standard ionization chamber dosimeters.
In intracavitary radiotherapy, incorrect source locations can result in excessive doses to normal tissues. Therefore, it is essential to accurately evaluate the source location. In this study, we investigated a digital line dosimeter based on thallium (I) bromide (TlBr) to improve the existing analogue verification method. Therefore, a polycrystalline TlBr unit cell dosimeter was manufactured, and the measurement performance of iridium-192 (Ir-192) sources was evaluated. We found that the dosimeter's reproducibility satisfied the evaluation criteria of 1.5% with a relative standard deviation of 1.44%. Moreover, the linearity showed excellent results (linear coefficient, R 2 = 0.9999). The distance dependence showed a difference of 0.03 cm at 50% intensity when compared to the inverse square value, whereas the angular dependence showed a large difference when compared to a diode. As the angle increased, the intensity gradually decreased, resulting in a difference of up to 41.9%. These results demonstrate the excellent performance of the TlBr dosimeter. However, because of the significant influence of angular dependence, a measurement distance that minimises this error should be applied when manufacturing line dosimeters in the future.
In radiotherapy, dose assessment is performed as part of quality assurance (QA) to verify the dose accuracy of the treatment administered to patients. Various dosimeters are used depending on the part of the body and the desired purpose, and tools such as the thermoluminescent dosimeter (TLD) and semiconductor dosimeter are used as in vivo dosimeters. However, TLDs have demonstrated measurement errors of approximately 11.8%, and the diodes used in semiconductor dosimeters fluctuate in performance owing to radiation damage. Consequently, various photoconductor materials are being researched to replace diodes. In particular, Thallium (I) bromide (TlBr) is being used as a substitute material for semiconductors because of its low cost and high performance. Therefore, this study determined the optimised performance of TlBr, which is a potential photoconductor material to replace other materials commercially, using the particle-in-binder deposition method. Upon evaluating the reproducibility and linearity, all sensors demonstrated remarkable performance at 6 MV and 15 MV as the results demonstrated a relative standard deviation (RSD) less than 1.5% and R2 value above 0.9998, which were the evaluation criteria. A 3:1 material ratio was chosen, as the performance demonstrated in this case was superior to that of other material ratios. The results of the monitor unit rate dependence and percent depth dose (PDD) were compared with those of silicon diode and thimble chambers, which are widely used for dose measurement. According to the monitor unit rate dependence results, the RSD was 0.66% at 6 MV and 0.27% at 15 MV with the standard set at 100 MU, indicating that the diode was outperformed by less than 1%. Similar results were obtained for the PDD with the ion chamber, and the surface dose required for in vivo dose measurement indicated an error within 8.67%. Therefore, this study provides basic data for polycrystalline TlBr dosimeters, which can replace the existing semiconductor dosimeters for QA.
Generally, electron therapy is applied to tumors on or close to the skin surface. However, this causes a variety of skin-related side effects. To alleviate the risk of these side effects, clinical treatment uses skin dosimeters to verify the therapeutic dose. However, dosimeters suffer from poor accuracy, because their attachment sites are approximated with the help of naked eyes. Therefore, a dosimeter based on a flexible material that can adjust to the contours of the human body is required. In this study, the reproducibility, linearity, dose-rate dependence, and percentage depth ionization (PDI) of PbO and HgO film-based dosimeters are evaluated to explore their potential as large-scale flexible dosimeters. The results demonstrate that both dosimeters deliver impressive reproducibility (within 1.5%) and linearity (≥ 0.9990). The relative standard deviations of the dose-rate dependence of the PbO and HgO dosimeters were 0.94% and 1.16% at 6 MeV, respectively, and 1.08% and 1.25% at 9 MeV, respectively, with the PbO dosimeter outperforming the 1.1% of existing diodes. The PDI analysis of the PbO and HgO dosimeters returned values of 0.014 cm (–0.074 cm) and 0.051 cm (–0.016 cm), respectively at 6 MeV (9 MeV) compared to the thimble chamber and R50. Therefore, the maximum error of each dosimeter is within the allowable range of 0.1 cm. In short, the analysis reveals that the PbO dosimeter delivers a superior performance relative to its HgO counterpart and has strong potential for use as a surface dosimeter. Thus, flexible monoxide materials have the necessary qualities to be used for dosimeters that meet the requisite quality assurance standards and can satisfy a variety of radiation-related applications as flexible functional materials.
Recently, cancer has been treated using high dose rates (HDRs), which requires highly reliable treatment plans. In current clinical practice, phosphors are widely used. However, these are of limited use for real-time verification of radiation during HDR brachytherapy; moreover, there is a possibility of electrical error via high-energy radiation because a photodiode is used to detect visible light. Therefore, it is necessary to develop a new dosimeter that can detect gamma rays effectively. This study aimed to investigate the feasibility of a lead monoxide- (PbO)-based dosimeter to detect the position of a radioactive source in HDR brachytherapy. It was confirmed that the fabricated PbO dosimeter has sufficient response coincidence, reproducibility, and dose linearity for gamma rays. Based on these results, it is demonstrated that the PbO dosimeter complies with the general requirements of HDR brachytherapy monitoring systems. Thus, the PbO dosimeter is expected to be used commercially in the future.
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