Here we report the catalytic oxidation of benzylic alcohol, hetero-aryl alcohols and propargylic alcohols to their corresponding carbonyl compound using heterobimetallic sodium-dioxidovanadium(V) complexes. The present catalytic oxidation studies proceed at 70°C using H 2 O 2 as terminal oxidant. During the whole process, the complexes react with hydrogen peroxide to form peroxovanadium(V) species. The present study shows the heterogeneity of pre-catalyst which could be easily recovered and moreover isolation of product is very simple.

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A palladium-catalyzed one-pot stepwise coupling-annulation reaction of 2-chloroqunoline-3-carbonitriles enabled the direct synthesis of sulfur-substituted benzo[b][1,6]naphthyridines via multiple bond formation. The reaction provided an unusual mode for cyclization as sodium sulfide, a soft nucleophile, preferred to attack on the carbon of the nitrile group rather than on the C-C triple bond. The developed chemistry was extended with the secondary amines as nucleophiles to afford nitrogen-substituted benzo[b][1,6]naphythyridines while primary amines afforded hydroamination products . The hydromination products were transformed to benzo[b][1,6]naphthyridones via a base-mediated cyclization reaction. The  developed protocol features inexpensive and easily synthesizable starting materials, easy operations, and a high efficiency and tolerance to a broad range of substrates.