BACKGROUND: Hypertension is the major risk factor for cardiovascular disease, a leading cause of premature death and disability. Interactive education and training are potentially used to improve hypertension knowledge. AIM: This study aimed to identify the impact of training and education programs toward knowledge in hypertension for women cadres. METHODS: This quasi-experimental study was conducted in Surabaya, Indonesia, involving 100 women cadre. The data were collected through interviews, pre- and post-training using a validated researcher-made questionnaire of demographic characteristics, and knowledge tests of hypertension. Data were analyzed using SPSS 21. RESULTS: Knowledge of cadre was significantly increased by 50% after the training and education program (p < 0.001). The median score of the pre-test and post-test was 40.00 (30.00–50.00) and 60.00 (50.00–70.00), respectively. The level of education found to have a negative correlation with the post-test score (p = 0.008). There was no difference in knowledge increment after training among age groups (p = 0.261), marital status (p = 0.849), or occupations type (p = 0.827). CONCLUSION: Training and education programs significantly improve the hypertension knowledge of woman cadre. This method can be a preferable early public health intervention to tackle hypertension.

Summary This study was conducted at a tertiary care centre of Delhi, to assess the magnitude of SARS-CoV-2 disease and outcome in pediatric surgical inpatients. All the admitted patients were evaluated excluding outpatients and minor procedures. Out of 312 operated patients 2.88% patients were SARS-CoV-2 positive and out of 167 non operative patients 6.58% were SARS-CoV-2 positive. These patients received standard care as per guidelines using standard protective measures and were discharged home. Only one death occurred due to perforation peritonitis with sepsis. The overall prevalence of SARS-CoV-2 in pediatric surgical patients was 4.17% and SARS-CoV-2 positive patients had similar outcomes as compared to non SARS-CoV-2 patients.

Septic embolism associated with infective endocarditis (IE) is the occlusion of a blood vessel caused by an infected thrombus traveling through the bloodstream resulting in ischemia and/or infarction. Septic embolism can result in ischemia and/or infarction due to vascular occlusion and infection, resulting in inflammation and possible abscess formation. Systemic embolization generally occurs in left-sided IE, causing stroke, blindness due to embolism or endophthalmitis, splenic or renal infarct, limb ischemia, or even acute myocardial infarction. Here, we report a case of acute on chronic limb-threatening ischemia due to septic embolism in patient with IE.

BACKGROUND: Changing of linear blood flow to turbulence at branching points predisposes to development of obstructive coronary lesions. We hypothesize that in addition to bifurcation angle (BA), proximal (PA) and third angle (TA) of branching site are important in generating more vertices of blood flow.METHODS: 65 normal and 36 significantly diseased LAD – D1, 72 normal and 27 significantly diseased LCX – OM, 73 normal and 16 significantly diseased RCA – PDA – PLV and 34 normal and 14 significantly diseased LMCA – LAD – LCX bifurcations were analyzed with QCA.RESULTS: In LAD – D1 normal vs. significantly diseased bifurcations BA and PA were 78.2±13.2 vs. 65.1±11.3 (p <0.000) and 122.7±13.8 vs. 131.6.36±12.5 (p <0.001) respectively. In LCX – OM normal vs. significantly diseased bifurcations BA and PA were 76.8±13.6 vs. 60.7±13.8 (p=0.000) and 125.1±13.5 vs. 137.8±12.8 (p <0.000) respectively. In RCA - PDA – PLV normal vs. significantly diseased bifurcations BA, PA and TA were 91.1±13.8 vs. 71.5±15.9 (p 0.004), 113.0±14.1 vs. 128.4±20.2 (p=0.000), 118.2±21.7 vs. 133.8±12.4 (p=0.007) respectively. In LMCA –LAD – LCX normal vs. significantly diseased bifurcations BA, PA and TA were 84.0±39.1 vs. 73.0±17.6 (p >0. 32), 123.2±26.3 vs. 115.3±30.4 (p > 0.38), 130.3±27.3 vs. 137.5±33.5 (p >0.45) respectively. There was a significant difference but no correlation between the angles in normal and diseased bifurcation segment. We derived logistic regression equations for predicting the disease in different coronary bifurcations.CONCLUSION: In LAD - D1, LCX – OM and RCA – PDA – PLV bifurcations lesser the BA, greater the PA, were more likely to develop significant lesion, which was not true in LMCA – LAD – LCX bifurcation.