Background The exhaustive information about non-communicable diseases associated with COVID-19 and severe acute respiratory syndrome corona virus-2 (SARS-CoV-2) are getting easier to find in the literature. However, there is a lack of knowledge regarding tuberculosis (TB) and chronic obstructed pulmonary disease (COPD), with numerous infections in COVID-19 patients. Objectives Priority is placed on determining the patient’s prognosis based on the presence or absence of TB and COPD. Additionally, a comparison is made between the risk of death and the likelihood of recovery in terms of time in COVID-19 patients who have either COPD or TB. Methodology At the DHQ Hospital in Muzaffargarh, Punjab, Pakistan, 498 COVID-19 patients with TB and COPD were studied retrospectively. The duration of study started in February 2022 and concluded in August 2022. The Kaplan–Meier curves described time-to-death and time-to-recovery stratified by TB and COPD status. The Wilcoxon test compared the survival rates of people with TB and COPD in two matched paired groups and their status differences with their standard of living. Results The risk of death in COVID-19 patients with TB was 1.476 times higher than in those without (95% CI: 0.949–2.295). The recovery risk in COVID-19 patients with TB was 0.677 times lower than in those without (95% CI: 0.436–1.054). Similarly, patients with TB had a significantly shorter time to death ( p =.001) and longer time to recovery ( p =.001). Conclusions According to the findings, the most significant contributor to an increased risk of morbidity and mortality in TB and COPD patients was the COVID-19. KEY MESSAGES SARS-Cov-19 is a new challenge for the universe in terms of prevention and treatment for people with tuberculosis and chronic obstructive pulmonary disease, among other diseases. Propensity score matching to control for potential biases. Compared to hospitalized patients with and without (TB and COPD) had an equivalently higher mortality rate.
Objectives: Chronic obstructive pulmonary disease (COPD) affects a large part of the population around the world between the ages forty-one to seventy-one years. However, by combining the effects of the COVID-19 pandemic and the SARS-Cov-2 virus on COPD patients, we may be able to overcome factors that have a significant impact on our success. Moreover, we have to investigate the relationship between the diagnosis and its influencing factors to possibly overcome the emerging causes of this disease. Methods: A retrospective study of 280 patients was conducted at DHQ Hospital Muzaffargarh in Punjab, Pakistan. Negative binomial regression describes the risk of fixed successive variables. Cox proportional hazard model, and the model co-efficient is observed using log-likelihood. Kaplan-Meier curves showed how long COPD patients survived or died. Results: The increased risk of death in COPD patients was due to the effects of variables such as cough, lower respiratory tract infection, tuberculosis, and body aches being 1.369, 0.693, 0.170, and 0.217 times higher, while it decreased by 0.396 in normal conditions. Conclusion: We found that the symptoms of COPD (cough, lower respiratory tract infection, tuberculosis, and body aches) are statistically significant in patients who were most infected by COVID-19 and SARS-Cov-2.
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