Berdasarkan data situasi dan analisis gizi di Indonesia pada tahun 2017, status gizi balita diukur dengan indeks tinggi badan per umur (TB/U). Provinsi dengan persentasebalita pendek dan sangat pendek terbesar adalah Kalimantan Barat (32,5%) dan terendah adalah Sumatera Selatan (14,2%). Tujuan dari penelitian ini adalah untuk mengetahui faktor-faktor yang mempengaruhi tumbuh kembang anak usia 4-6 tahun di desa kuala 2 wilayah kerja Puskesmas Sungai Durian. Penelitian ini adalah penelitian observasional analitik dengan desain cross sectional. Populasi dalam penelitian ini berjumlah 242 orang. Sampel dalam penelitian ini berjumlah 69 orang anak usia 4-6 tahun, diambil menggunakan random sampling serta menggunakan uji statistik chi-square. Hasil penelitian menunjukan faktor yang berhubungan dengan pertumbuhan anak berdasarkan indikator TB/U, yaitu riwayat ASI eksklusif (p=0,004) berat badan lahir rendah (BBLR) (p=0,003), imunisasi dasar (p=0,000), penyakit infeksi (p=0,000). Sedangkan faktor yang tidak berhubungan dengan pertumbuhan anak berdasarkan indikator TB/U yaitu usia saat hamil (p=0,103). Serta terdapat hubungan yang signifikan antara pertumbuhan anak berdasarkan indikator TB/U dengan perkembangan anak (p=0,000).Saran kepada Puskesmas Sungai Durian untuk melakukan kegiatan sosialisasi di masyarakat serta membuat program khususnya tentang pentingnya deteksi dini gangguan tumbuh kembang anak, sehingga diharapkan dapat mengatasi gangguan tumbuh kembang anak di wilayah kerja puskesmas.   According to the Indonesian ministry of health, 2017 the nutritional status of children under five as measured by the height per age index, the province with the largest proportion of short and very short children under five is West Kalimantan (32.5% ) and the lowest was South Sumatra (14.2%). The purpose of this study was to determine the factors that influence the growth and development of children aged 4-6 years in Kuala Village 2, the working area of Sungai Durian Health Center. This study was an observational analytic study with a cross sectional design. The population in this study was probably 242 people. The sample in this study may be 69 children aged 4-6 years, taken using random sampling and using chi-square test statistics. The results showed the factors associated with growth based on the indicator of height / age, namely a history of exclusive breastfeeding (p = 0.004), low birth weight (LBW) (p=0.003), basic immunization (p=0.000), infectious diseases (p = 0.000). Meanwhile, the factor that was not related to children's growth based on the indicator of height / age was the age at pregnancy (p = 0.103). As well as the significant relationship variable between children's growth based on the indicator of height / age with child development (p=0.000) It is suggested to Sungai Durian Public Health Center to carry out socialization activities in the community and create a program specifically on the importance of early detection of child developmental disorders, so that it is hoped that it can overcome child development disorders in the working area of the puskesmas.